[HTML][HTML] Therapy-induced senescence through the redox lens
Therapy-induced senescent tumor cells have emerged as significant drivers of tumor
recurrence and disease relapse. Interestingly, reactive oxygen species (ROS) production …
recurrence and disease relapse. Interestingly, reactive oxygen species (ROS) production …
Nanocarriers for natural polyphenol senotherapeutics
N Joma, PB Bielawski, A Saini, A Kakkar… - Aging …, 2024 - Wiley Online Library
Senescence is a heterogenous and dynamic process in which various cell types undergo
cell‐cycle arrest due to cellular stressors. While senescence has been implicated in aging …
cell‐cycle arrest due to cellular stressors. While senescence has been implicated in aging …
Post-acute sequelae of SARS-CoV-2 infection (Long COVID) in older adults
SJ Russell, K Parker, A Lehoczki, D Lieberman… - GeroScience, 2024 - Springer
Long COVID, also known as PASC (post-acute sequelae of SARS-CoV-2), is a complex
infection-associated chronic condition affecting tens of millions of people worldwide. Many …
infection-associated chronic condition affecting tens of millions of people worldwide. Many …
Risk factors of using late-autophagy inhibitors: Aspects to consider when combined with anticancer therapies
M Skrzeszewski, M Maciejewska, D Kobza… - Biochemical …, 2024 - Elsevier
Cancer resistance to therapy is still an unsolved scientific and clinical problem. In 2022, the
hallmarks of cancer have been expanded to include four new features, including cellular …
hallmarks of cancer have been expanded to include four new features, including cellular …
Therapy-induced senescence is finally escapable, what is next?
T Saleh - Cell Cycle, 2024 - Taylor & Francis
Several breakthrough articles have recently confirmed the ability of tumor cells to escape the
stable cell cycle arrest imposed by Therapy-Induced Senescence (TIS). Subsequently …
stable cell cycle arrest imposed by Therapy-Induced Senescence (TIS). Subsequently …
Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia
AJ Stuart, T de Lange - bioRxiv, 2024 - biorxiv.org
Programmed telomere shortening limits tumorigenesis through the induction of replicative
senescence. Here we address three long-standing questions concerning senescence. First …
senescence. Here we address three long-standing questions concerning senescence. First …