Biophysical insight into the binding mechanism of doxofylline to bovine serum albumin: An in vitro and in silico approach

S Siddiqui, F Ameen, T Kausar, SM Nayeem… - … Acta Part A: Molecular …, 2021 - Elsevier
Insight into the mechanistic binding of bovine serum albumin (BSA) with doxofylline can
layout pivotal enlightenment with relevance to pharmacokinetics and pharmacodynamics …

Albumin roles in developing anticancer compounds

AG Ribeiro, JEF Alves, JCS Soares… - Medicinal Chemistry …, 2021 - Springer
Albumin is an abundant protein in nature with several biological functions. In the human
body, both in health and in illness, its transport function is highlighted by the binding to …

Characterization of the binding interaction between atrazine and human serum albumin: Fluorescence spectroscopy, molecular dynamics and quantum biochemistry

VLB França, JL Amaral, YA Martins… - Chemico-Biological …, 2022 - Elsevier
Atrazine (ATR), one of the most used herbicides worldwide, causes persistent contamination
of water and soil due to its high resistance to degradation. ATR is associated with low fertility …

Interaction mechanism of a pesticide, Azoxystrobin with bovine serum albumin: Assessments through fluorescence, UV–Vis absorption, electrochemical and molecular …

C Erkmen, I Celik - Spectrochimica Acta Part A: Molecular and …, 2024 - Elsevier
The current study's objective was to investigate how an antifungal pesticide Azoxystrobin
(AZO) interacts with bovine serum albumin (BSA) under conditions that simulate a …

Synthesis and characterization of 1-phenylisatin incorporated chitosan/PEG nanoparticles: Interaction with bovine serum albumin and application in drug delivery

N Rahman, N Khalil - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
This study details the synthesis, characterization and protein binding efficiency of chitosan
nanoparticles. Chitosan (CS) supported 1-phenylisatin (1-ph) loaded CS nanoparticles …

Molecular docking and muiltple spectroscopy investigation on the binding characteristics of aloe-emodin to pepsin

G Ren, H Sun, G Li, J Fan, Y Wu, G Cui - Journal of molecular structure, 2019 - Elsevier
In this study, the binding characteristics of aloe-emodin (AE) and pepsin were investigated
via multiple spectroscopic and molecular docking methods. The Stern-Volmer quenching …

Antitumor and antioxidant activities of purple potato ethanolic extract and its interaction with liposomes, albumin and plasmid DNA

P Strugała, A Urbaniak, P Kuryś, A Włoch, T Kral… - Food & Function, 2021 - pubs.rsc.org
The aim of the study was to broadly determine the biological activities of purple potato
ethanolic extract of the Blue Congo variety (BCE). The antioxidant activity of BCE was …

Human serum albumin-occupying-based fluorescence turn-on analysis of antiepileptic drug tiagabine hydrochloride

Z Zou, X Liao, L Yang, Z Huang, H Yang… - Analytical …, 2020 - ACS Publications
Tiagabine hydrochloride (TGB) is a clinically frequently used drug for anticonvulsion and
reducing epileptic frequency. Over administration of TGB could bring about adverse effects …

A Novel Fluorescent Probe for the Detection of Cyanide Ions in Solutions and Studies on Its Biophysical Interactions with ctDNA and Proteases

B Doyuran, E Gökoğlu, A Zouitini, E Keleş… - Journal of …, 2022 - Springer
A new cationic indolium based styryl dye (Ci) as a fluorescent probe was synthesized and its
anions selectivity/sensitivity properties/molecular interactions with protease enzymes …

Exploring the binding mechanism and adverse toxic effects of chiral phenothrin to human serum albumin: Based on multi-spectroscopy, biochemical and …

Y Gao, C Bian, N Li, K Yao, L Xiao, Z Yang… - Spectrochimica Acta Part …, 2022 - Elsevier
To understand the binding mechanism of a mixture of chiral phenothrin with human serum
albumin (HSA), we used multi-spectroscopy, including steady-state fluorescence …