Abstract L‐3, 4‐Dihydroxyphenylalanine (L‐DOPA) is the most effective drug in the
symptomatic treatment of Parkinson's disease, but chronic use is associated with L‐DOPA …

Parkinson's disease is associated with high treatment costs, primarily attributed to the needs
of hospitalization and frequent care services. A study reveals annual per-person healthcare …

Objective To identify markers of resistance to developing Parkinson disease (PD) among
LRRK2 mutation carriers (LRRK2+), we carried out metabolomic profiling in individuals with …

There is mounting evidence for the potential for the natural dietary antioxidant and anti-
inflammatory amino acid l-Ergothioneine (ERGO) to prevent or mitigate chronic diseases of …

Parkinson's disease (PD) shows high heterogeneity with regard to the underlying molecular
pathogenesis involving multiple pathways and mechanisms. Diagnosis is still challenging …

Ergothioneine is a naturally occurring amino acid and thiol antioxidant found in high
amounts in mushrooms and fermented foods. Humans and animals acquire ergothioneine …

Background: Emerging evidence suggests that gut dysbiosis contributes to Parkinson's
disease (PD) by signaling through microbial metabolites. Hippuric acid (HA), indole …

Ergothioneine (ERG), is a water-soluble amino acid that is derived entirely from dietary
sources. It has received much attention as a therapeutic agent due to its anti-oxidant …

Recent evidence confirms that PD is indeed a multifactorial disease with different aetiologies
and prodromal symptomatology that likely depend on the initial trigger. New players with …

We propose that the diet-derived compound ergothioneine (ET) is an important nutrient in
the human body, especially for maintenance of normal brain function, and that low body ET …