New cocrystals of heterocyclic drugs: structural, antileishmanial, larvicidal and urease inhibition studies

G Murtaza, M Khan, S Farooq… - … Section C: Structural …, 2023 - journals.iucr.org
Many heterocycles have been developed as drugs due to their capacity to interact
productively with biological systems. The present study aimed to synthesize cocrystals of the …

Non-Covalent Reactions Supporting Antiviral Development

I Nugrahani, E Susanti, T Adawiyah, S Santosa… - Molecules, 2022 - mdpi.com
Viruses are the current big enemy of the world's healthcare systems. As the small infector
causes various deadly diseases, from influenza and HIV to COVID-19, the virus continues to …

[PDF][PDF] Carvedilol solubility enhancement by multicomponent crystallization with coformers of benzoic acid, isonicotinamide, and saccharin

I Sopyan, RT Layyareza, S Megantara… - Pharmacia, 2023 - pharmacia.pensoft.net
Multicomponent crystallization is a method that can modify the physicochemical properties of
Carvedilol (CVD), thereby increasing its solubility. Based on in silico screening the …

Optical and calorimetric studies of quercetin-doped liquid crystals: Effects of molecular aggregation

AN Samoilov, SS Minenko, OY Sushynskyi… - Journal of Molecular …, 2019 - Elsevier
The organic substance quercetin, when added to liquid crystal (LC) systems as non-
mesogenic dopant significantly affects properties of the LC host. The microphotographs of …

The Effect of pH and Cocrystal Quercetin-Isonicotinamide on Quercetin Solubility and its Thermodynamic

B Wisudyaningsih, S Sallama… - Research Journal of …, 2021 - indianjournals.com
This study aimed to improve the solubility of quercetin by solvent pH control method and
crystal modification through co-crystal formation using isonicotinamide as its co-former …

[PDF][PDF] Utilizing hot-stage polarized microscopy and ATR-FTIR for ramipril co-crystal screening, supported by principal component analysis and cluster analysis

I Indra, S Wikarsa, YP Nugraha, V Suendo… - Journal of Pharmacy & …, 2023 - jppres.com
Context: Co-crystal formation, a method for enhancing the physicochemical properties of
active pharmaceutical ingredients (APIs), has gained traction in pharmaceutical research …

[HTML][HTML] Cocrystallization of Active Pharmaceutical Ingredients Derived from Traditional Chinese Medicines

H Guo, S Liu - Chemical and Pharmaceutical Bulletin, 2023 - jstage.jst.go.jp
This review highlights the cocrystals of active pharmaceutical ingredients (APIs) derived
from traditional Chinese medicines (TCMs) in categories,∆ pK a rule, preparation …

Multicomponent Crystal Formation of Dexibuprofen-Caffeine to Improve Solubility

F Alatas, GK Pratiwi, H Meylifepri - Tropical Journal of Natural Product …, 2023 - ajol.info
Alteration of solid form via a multicomponent crystal formation can be a choice to improve
the solubility of a poor solubility drug, such as dexibuprofen. The purpose of this research …

Preparation and Physicochemical Characterizations of p-Methoxycinnamic acid–Succinic Acid Cocrystal by Solvent Evaporation Technique

MI Sulistyowaty, D Setyawan, R Sari… - … Macedonian Journal of …, 2022 - oamjms.eu
Background: PMCA (p-Methoxycinnamic acid) is an active pharmaceutical ingredient
derived from Kaempheria galanga L (known as kencur in Indonesia), which is poorly soluble …

Obtenção e caracterização de novas dispersões sólidas do antimicrobiano claritromicina

DS LUZ - 2022 - tedebc.ufma.br
RESUMO A Claritromicina (CLA) é um antibiótico utilizado para o tratamento de doenças
causadas por bactérias, tal como a hanseníase. A CLA pertence à Classe II do sistema de …