Approach to COVID-19 in older adults and indications for improving the outcomes

C Tana, L Moffa, K Falasca, J Vecchiet, M Tana… - Annals of …, 2023 - Taylor & Francis
Background: COVID-19 continues to present challenges in the care of older adults with
frailty and/or comorbidities and very old patients, who can be hospitalized with severe …

[HTML][HTML] To Be Frail or Not to Be Frail: This Is the Question—A Critical Narrative Review of Frailty

S Sciacchitano, V Carola, G Nicolais… - Journal of Clinical …, 2024 - mdpi.com
Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …

[HTML][HTML] Mortality and risk factors of vaccinated and unvaccinated frail patients with COVID-19 treated with anti-SARS-CoV-2 monoclonal antibodies: A real-world study

R Nevola, G Feola, R Ruocco, A Russo, A Villani… - International Journal of …, 2023 - Elsevier
Objectives There is a scarcity of data on the outcomes and predictors of therapeutic failure of
monoclonal antibodies (mAbs) in frail patients with COVID-19. Methods Prospective study …

[HTML][HTML] Development and validation of an electronic database-based frailty index to predict mortality and hospitalization in a population-based study of adults with …

P Rebora, CA Scirè, G Occhino, F Bortolan… - Frontiers in …, 2023 - frontiersin.org
Background Electronic health databases are used to identify people at risk of poor
outcomes. Using electronic regional health databases (e-RHD), we aimed to develop and …

[HTML][HTML] Association between multidimensional prognostic index (MPI) and infections in a population of older people affected by COVID-19

FS Ragusa, L Solimando, C Mandalà… - Aging Clinical and …, 2023 - Springer
Background Only limited studies analyzed a possible relationship between frailty and
infections. Our aim was to investigate the possible association between higher …

[HTML][HTML] Nirmatrelvir/Ritonavir Utilization for the Treatment of Non-hospitalized Adults with COVID-19 in the National Veterans Affairs (VA) Healthcare System

HJ Appaneal, KL LaPlante, VV Lopes, C Martin… - Infectious Diseases and …, 2024 - Springer
Methods We conducted a retrospective cohort study among outpatients with coronavirus
disease 2019 (COVID-19) who were eligible to receive nirmatrelvir/ritonavir between …

Effect of the implementation of clinical guidelines on management of candidemia in elderly patients

NV Lopez, JC Parra, AM Serrano, AG Villanueva… - Mycoses, 2023 - Wiley Online Library
Introduction Mortality from candidemia is higher in elderly population than in younger
patients, which may be related to suboptimal management. The aim of the present study is to …

[HTML][HTML] An epidemiological survey of COVID-19 serology and its association with clinical infection among older adults–does antibody titer matter?

DS Shapiro, R Ellis, J Zidan, Y Wiener-Well, M Bar-Meir… - BMC geriatrics, 2024 - Springer
Background Older adults are at increased risk of severe SARS-CoV-2 infection. In this study
we assessed the response to COVID-19 vaccination and infection rates among nursing …

Serial SOFA‐score trends in ICU‐admitted COVID‐19 patients as predictor of 28‐day mortality: A prospective cohort study

F Esmaeili Tarki, S Afaghi, FS Rahimi… - Health Science …, 2023 - Wiley Online Library
Abstract Background and Aim The efficacy of Sequential Organ Failure Assessment (SOFA)
score as predictor of clinical outcomes among ICU‐admitted COVID‐19 patients is still …

The impact of the COVID-19 pandemic on the length of management of polytraumatized patients in the emergency department

N Neskovic, D Klepo, T Janosevic… - Disaster and …, 2023 - journals.viamedica.pl
INTRODUCTION: The personal protective equipment used by healthcare workers and
special institutional protocols during the COVID-19 pandemic could potentially slow down …