Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Glioblastoma (GB) tumors are one of the most insidious cancers which take over the brain
and defy therapy. Over time and in response to treatment the tumor and the brain cells in the …

Background Despite advancements in the successful use of immunotherapy in treating a
variety of solid tumors, applications in treating brain tumors have lagged considerably. This …

Background The tumor microenvironment (TME) has a central role in the oncogenesis of
osteosarcomas. The composition of the TME is essential for the interaction between tumor …

Glioblastoma is a lethal brain cancer with treatment resistance stemming from its interactions
with the surrounding microenvironment and obstacles such as the blood–brain barrier …

Advancing personalized medicine in brain cancer relies on innovative strategies, with
mRNA vaccines emerging as a promising avenue. While the initial use of mRNA vaccines …

Glioblastoma is a deadly brain tumor without any significantly successful treatments to date.
Tumor antigen-targeted immunotherapy platforms including peptide and dendritic cell (DC) …

Glioblastoma is highly aggressive and remains difficult to treat despite being the most
common malignant primary brain tumor in adults. Current standard-of-care treatment calls …

Background: Pediatric gliomas (PGs) are highly aggressive and predominantly occur in
young children. In pediatric gliomas, abnormal expression of Homeobox (HOX) family genes …

Glioblastoma (GBM) is the most typical and aggressive form of primary brain tumor in adults,
with a poor prognosis. Successful glioma treatment is hampered by ineffective medication …