COVID‐19: Virology, biology and novel laboratory diagnosis

M Mohamadian, H Chiti, A Shoghli… - The journal of gene …, 2021 - Wiley Online Library
Background At the end of December 2019, a novel coronavirus tentatively named SARS‐
CoV‐2 in Wuhan, a central city in China, was announced by the World Health Organization …

Therapeutic potential of pyrrole and pyrrolidine analogs: an update

N Jeelan Basha, SM Basavarajaiah, K Shyamsunder - Molecular Diversity, 2022 - Springer
The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …

Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective

S Halawa, SS Pullamsetti, CRM Bangham… - Nature Reviews …, 2022 - nature.com
The lungs are the primary target of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection, with severe hypoxia being the cause of death in the most critical cases …

Role of histone post-translational modifications in inflammatory diseases

Y Lin, T Qiu, G Wei, Y Que, W Wang, Y Kong… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a defensive reaction for external stimuli to the human body and generally
accompanied by immune responses, which is associated with multiple diseases such as …

COVID-19 and vaccination: myths vs science

VP Chavda, Y Chen, J Dave, ZS Chen… - Expert Review of …, 2022 - Taylor & Francis
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …

The epigenetic implication in coronavirus infection and therapy

S Atlante, A Mongelli, V Barbi, F Martelli, A Farsetti… - Clinical …, 2020 - Springer
Epigenetics is a relatively new field of science that studies the genetic and non-genetic
aspects related to heritable phenotypic changes, frequently caused by environmental and …

Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus1

TH Beacon, GP Delcuve, JR Davie - Genome, 2021 - cdnsciencepub.com
The angiotensin-converting enzyme 2 (ACE2) is the receptor for the three coronaviruses
HCoV-NL63, SARS-CoV, and SARS-CoV-2. ACE2 is involved in the regulation of the renin …

Thymoquinone: A promising natural compound with potential benefits for COVID-19 prevention and cure

OA Badary, MS Hamza, R Tikamdas - Drug design, development …, 2021 - Taylor & Francis
COVID-19 has caused a major global health crisis, as excessive inflammation, oxidation,
and exaggerated immune response in some sufferers can lead to a condition known as …

Dysregulated interferon response underlying severe COVID-19

LA Lopez, PC Sang, Y Tian, Y Sang - Viruses, 2020 - mdpi.com
Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral
mechanisms. Recent studies reveal that IFN dysregulation is key to determine COVID-19 …

Gender specific differences in disease susceptibility: the role of epigenetics

L Migliore, V Nicoli, A Stoccoro - Biomedicines, 2021 - mdpi.com
Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …