Immunosenescence increases the risk and severity of diseases in elderly individuals and
leads to impaired vaccine-induced immunity. With aging of the global population and the …

Abstract Background Coronavirus disease 2019 (COVID-19) remains a threat to vulnerable
populations such as long-term care facility (LTCF) residents, who are often older, severely …

Background. Several Canadian provinces are extending the interval between COVID-19
vaccine doses to increase population vaccine coverage more rapidly. However …

Purpose To investigate breast cancer survivors' inflammatory responses to typhoid vaccine
as a window into their innate immune response to novel pathogens. Methods This double …

Despite the reported sex-related variations in the immune response to vaccination, whether
the effects of SARS-CoV-2 vaccination differ by sex is still under debate, especially …

Rapid growth of the geriatric population has been made possible with advancements in
pharmaceutical and health sciences. Hence, age-associated diseases are becoming more …

Background The loss in age-related immunological markers, known as immunosenescence,
is caused by a combination of factors, one of which is inflammaging. Inflammaging is …

Increasing evidence shows that some probiotics can improve vaccine responses as
adjuvants. This study aimed to evaluate the effect of Pediococcus pentosaceus MIANGUAN …

Introduction Most existing vaccines require higher or additional doses or adjuvants to
provide similar protection for people living with HIV (PLWH) compared with HIV-uninfected …

Vaccine development targeting SARS-CoV-2 in 2020 was of critical importance in reducing
COVID-19 severity and mortality. In the UK during the initial roll-out most individuals either …