Sex differences in the efficacy and safety of SARS-CoV-2 vaccination in residents of long-term care facilities: insights from the GeroCovid Vax study

C Trevisan, V Raparelli, A Malara… - Internal and Emergency …, 2023 - Springer
Despite the reported sex-related variations in the immune response to vaccination, whether
the effects of SARS-CoV-2 vaccination differ by sex is still under debate, especially …

Potential of mesenchymal stem cells in the rejuvenation of the aging immune system

GEC Yeo, MH Ng, FB Nordin, JX Law - International journal of molecular …, 2021 - mdpi.com
Rapid growth of the geriatric population has been made possible with advancements in
pharmaceutical and health sciences. Hence, age-associated diseases are becoming more …

“Just right” combinations of adjuvants with nanoscale carriers activate aged dendritic cells without overt inflammation

A Ananya, KG Holden, Z Gu, D Nettleton… - Immunity & …, 2023 - Springer
Background The loss in age-related immunological markers, known as immunosenescence,
is caused by a combination of factors, one of which is inflammaging. Inflammaging is …

Pediococcus pentosaceus MIANGUAN Enhances the Immune Response to Vaccination in Mice

Y Chen, Z Cao, S Lu, Z Wang, C Ma, G Zhang… - Probiotics and …, 2024 - Springer
Increasing evidence shows that some probiotics can improve vaccine responses as
adjuvants. This study aimed to evaluate the effect of Pediococcus pentosaceus MIANGUAN …

CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort study

CT Costiniuk, J Singer, MA Langlois, I Kulic… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Most existing vaccines require higher or additional doses or adjuvants to
provide similar protection for people living with HIV (PLWH) compared with HIV-uninfected …

Influence of individuals' determinants including vaccine type on cellular and humoral responses to SARS-CoV-2 vaccination

ES Chambers, W Cai, G Vivaldi, DA Jolliffe, N Perdek… - npj Vaccines, 2024 - nature.com
Vaccine development targeting SARS-CoV-2 in 2020 was of critical importance in reducing
COVID-19 severity and mortality. In the UK during the initial roll-out most individuals either …

[HTML][HTML] The non-saponin fraction of Korean Red Ginseng ameliorates sarcopenia by regulating immune homeostasis in 22–26-month-old C57BL/6J mice

HJ Oh, H Jin, BY Lee - Journal of Ginseng Research, 2022 - Elsevier
Background The non-saponin fraction (NSF) of Korean Red Ginseng is a powder in which
saponin is eliminated from red ginseng concentrate by fractionation. In this study, we …

Terminally differentiated effector memory T cells associate with cognitive and AD-related biomarkers in an aging-based community cohort

E Winford, J Lutshumba, BJ Martin, DM Wilcock… - Immunity & …, 2024 - Springer
Background and purpose The immune response changes during aging and the progression
of Alzheimer's disease (AD) and related dementia (ADRD). Terminally differentiated effector …

Exposure to perfluoroalkyl substances and neonatal immunoglobulin profiles in the upstate KIDS study (2008–2010)

LE Jones, A Ghassabian, DA Lawrence… - Environmental …, 2022 - Elsevier
Infant exposure to per/polyfluoroalkyl compounds is associated with immune disruption. We
examined associations between neonatal concentrations of perflurooctanoic acid (PFOA) …

[HTML][HTML] Host immune responses and possible therapeutic targets for viral respiratory tract infections in susceptible populations: a narrative review

PC Fragkou, CD Moschopoulos, R Reiter… - Clinical Microbiology …, 2022 - Elsevier
Background Respiratory viruses are associated with significant global morbidity and
mortality, as well as socioeconomic factors. Certain conditions and patient groups are more …