In the context of an ageing population, one of the major Public Health goals is to promote
healthy ageing. To rise to this challenge, rethinking conventional prevention paradigms and …

The health problems associated with the aging process are becoming increasingly
widespread due to the increase in mean life expectancy taking place globally. While decline …

Objectives The immunogenicity of the Comirnaty® vaccine against coronavirus disease
2019 (COVID-19) has not been adequately studied in elderly people with comorbidities. We …

The discovery of vaccines has enabled the successful prevention of many deadly infectious
diseases, decreased the overall mortality rate, and improved life expectancy worldwide [1] …

Objectives: Many vaccines require higher/additional doses or adjuvants to provide adequate
protection for people with HIV (PWH). Here, we compare coronavirus disease 2019 (COVID …

Respiratory viral infections frequently lead to severe respiratory disease, particularly in
vulnerable populations such as young children, individuals with chronic lung conditions and …

Introduction Disease-modifying therapies (DMTs) have been shown to improve disease
outcomes in multiple sclerosis (MS) patients. They may also impair the immune response to …

Despite the availability of licensed vaccines, pneumococcal disease caused by the bacteria
Streptococcus pneumoniae (pneumococcus), remains a serious infectious disease threat …

Aging induces numerous physiological alterations, with immunosenescence emerging as a
pivotal factor. This phenomenon has attracted both researchers and clinicians, prompting …

Background Immune responses to influenza vaccination tend to be lower among older,
frequently vaccinated adults. Use of egg-free influenza vaccines is increasing, but limited …