Although hepatitis B virus (HBV) vaccination is recommended for hepatitis C virus (HCV)-
infected individuals to avoid HBV superinfection, the persistence of their humoral and cell …

Objective Epidemiological studies suggest that consumption of fruits and vegetables (FV) is
negatively associated with the incidence of certain cancers and mortality. However, a causal …

Objectives: Many vaccines require higher/additional doses or adjuvants to provide adequate
protection for people living with HIV (PLWH). Here, we compare COVID-19 vaccine-induced …

Vaccine development targeting SARS-CoV-2 in 2020 was of critical importance in reducing
COVID-19 severity and mortality. In the UK during the initial roll-out most individuals either …

CD4+ T cells are essential for protection from viral pathogens, such as SARS-CoV-2.
However, an increase in the dysfunction CD4+ EMRA subset is likely to hinder the immune …

Vaccination-induced protection against influenza is greatly diminished and increasingly
heterogeneous with age. We investigated longitudinally (up to five timepoints) a cohort of …

Background: This umbrella review aims to synthesize the existing literature on the
preventive and therapeutic benefits of minerals zinc, selenium, iron, copper, magnesium …

Aging is a series of processes that are controlled by a genetic sequence and cause
structural and functional changes in the organism that eventually cause it to die. Population …

Monogenic diseases are often studied in isolation due to their rarity. Here we utilize
multiomics to assess 22 monogenic immune-mediated conditions with age-and sex …

The renin angiotensin system (RAS) is composed of several enzymes and substrates on
which angiotensin converting enzyme (ACE) and renin act to produce angiotensin II. ACE …