A review: Highlighting the links between epigenetics, COVID-19 infection, and vitamin D

A Foolchand, S Mazaleni, T Ghazi… - International Journal of …, 2022 - mdpi.com
The highly transmittable and infectious COVID-19 remains a major threat worldwide, with the
elderly and comorbid individuals being the most vulnerable. While vaccines are currently …

Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination

APS Pang, AT Higgins-Chen, F Comite, I Raica… - Frontiers in …, 2022 - frontiersin.org
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …

A methylation clock model of mild SARS‐CoV‐2 infection provides insight into immune dysregulation

W Mao, CM Miller, VD Nair, Y Ge… - Molecular Systems …, 2023 - embopress.org
DNA methylation comprises a cumulative record of lifetime exposures superimposed on
genetically determined markers. Little is known about methylation dynamics in humans …

Single-cell multiomics revealed the dynamics of antigen presentation, immune response and T cell activation in the COVID-19 positive and recovered individuals

P Chattopadhyay, K Khare, M Kumar, P Mishra… - Frontiers in …, 2022 - frontiersin.org
Introduction Despite numerous efforts to describe COVID-19's immunological landscape,
there is still a gap in our understanding of the virus's infections after-effects, especially in the …

Epigenetic rewiring of pathways related to odour perception in immune cells exposed to SARS-CoV-2 in vivo and in vitro

J Huoman, S Sayyab, E Apostolou, L Karlsson… - Epigenetics, 2022 - Taylor & Francis
ABSTRACT A majority of SARS-CoV-2 recoverees develop only mild-to-moderate
symptoms, while some remain completely asymptomatic. Although viruses, including SARS …

Dynamic transcriptome analyses reveal m6A regulated immune non-coding RNAs during dengue disease progression

Y Zhang, J Guo, Y Gao, S Li, T Pan, G Xu, X Li, Y Li… - Heliyon, 2023 - cell.com
Dengue infection is one of the most prevalent arthropod-borne viral diseases, which can
result in severe complications. Identification of genes and long non-coding RNAs (lncRNAs) …

Role of epigenetics in the clinical evolution of COVID-19 disease. Epigenome-wide association study identifies markers of severe outcome

L Calzari, L Zanotti, E Inglese, F Scaglione… - European Journal of …, 2023 - Springer
Background COVID-19 has a wide spectrum of clinical manifestations and given its impact
on morbidity and mortality, there is an unmet medical need to discover endogenous cellular …

Potential links between COVID-19 and periodontitis: A bioinformatic analysis based on GEO datasets

C Zhang, Y Sun, M Xu, C Shu, Z Yue, J Hou, D Ou - BMC Oral Health, 2022 - Springer
Abstract Background 2019 Coronavirus disease (COVID-19) is an infectious disease caused
by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The COVID-19 …

EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection

Y Lee, E Riskedal, KT Kalleberg, M Istre, A Lind… - Scientific Reports, 2022 - nature.com
Although substantial progress has been made in managing COVID-19, it is still difficult to
predict a patient's prognosis. We explored the epigenetic signatures of COVID-19 in …

[HTML][HTML] Sarbecovirus disease susceptibility is conserved across viral and host models

SR Leist, A Schäfer, EL Risemberg, TA Bell, P Hock… - Virus Research, 2024 - Elsevier
Coronaviruses have caused three severe epidemics since the start of the 21 st century:
SARS, MERS and COVID-19. The severity of the ongoing COVID-19 pandemic and …