Precision medicine relies on the identification of robust disease and risk factor signatures
from omics data. However, current knowledge-driven approaches may overlook novel or …

Inflammatory bowel disease (IBD) is marked by persistent inflammation, and its development
and progression are linked to environmental, genetic, immune system and gut microbial …

The increasing concentration of Antimony (Sb) in ecological environments has raised
serious concerns about its potential biotoxicological impact. This study investigated the …

Dynamic changes in genomic DNA methylation patterns govern the epigenetic
developmental programs and accompany the organism's aging. Epigenetic clock (eAge) …

This study explores the transformative impact of Artificial Intelligence (AI) and Machine
Learning (ML) in healthcare, focusing on enhancing patient care through operational …

Background Diabetes cardiac fibrosis is associated with altered DNA methylation of
fibrogenic genes; however, the underlying mechanisms remain unclear. Objectives In this …

Aging-related DNA methylation changes are numerous. Their precise measurement has
opened new avenues to explore aging-related disease pathology, including the construction …

Background: Hepatocellular carcinoma (HCC) remains notorious for its high malignancy,
poor prognosis and high mortality. The exploration of novel therapeutic agents for HCC has …

Identifying disease-related biomarkers from high-dimensional DNA methylation data helps
in reducing early screening costs and inferring pathogenesis mechanisms. Good discovery …

Arsenic is a naturally occurring metal carcinogen found in the Earth's crust. Millions of
people worldwide are chronically exposed to arsenic through drinking water and food …