Type 2 diabetes mellitus (T2D) is a leading cause of disability and mortality in the United
States, and is responsible for $327 billion annually in economic damage. The presence of …

Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports
on work done with carcinogenic metals and the mechanisms of their carcinogenicity …

Movement disorders include monogenic modes of inheritance due to rare variants of large
effect size and polygenic forms involving many loci with mild effects. We identified variants in …

Leukaemia is the most common type of cancer found in children, with incidence rates
increasing. Chromosomal translocations are considered one of the leukaemia initiating …

This study systematically summarizes the importance and mechanism of DNA methylation in
epigenetic regulation of Pomeranians, providing in-depth insights into understanding the …

Abstract Localised Prostate Cancer (PCa) is a slow-growing and heterogenous disease,
with both indolent and aggressive phenotypes, which are very difficult to differentiate at …

Humans exhibit a diverse range of variations in complex traits including behaviors and
diseases. The trait variations within and between populations, also known as inter-individual …