Triple negative breast cancer (TNBC) is a heterogeneous group of breast cancers
characterized by their lack of estrogen receptors, progesterone receptors, and the HER2 …

Aortic dissection (AD) has an unfavorable prognosis. It requires early diagnosis, appropriate
treatment strategies, and suspicion to recognize symptoms; thus, it is commonly described …

Due to importance of developing insights into the related issues of drug delivery processes,
the beryllium oxide fullerene-like particles were investigated in this work the in the original …

NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …

Poly (ADP-ribose) polymerase inhibitors (PARPi) are selectively active in ovarian cancer
(OC) with homologous recombination (HR) deficiency (HRD) caused by mutations in …

DNA methylation is a fundamental epigenetic modification involved in various biological
processes and diseases. Analysis of DNA methylation data at a genome-wide and high …

G protein-coupled receptors (GPCRs) play a key role in regulating the homeostasis of the
internal environment and are closely associated with tumour progression as major …

Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Immunotherapy based on immune checkpoint inhibitors (ICIs) has revolutionized treatment
strategies in multiple types of cancer. However, the resistance and relapse as associated …

Epigenetic modifications are defined as heritable changes in gene activity that do not
involve changes in the underlying DNA sequence. The oncogenic process is driven by the …