[HTML][HTML] Peptide and peptide-based inhibitors of SARS-CoV-2 entry

D Schütz, YB Ruiz-Blanco, J Münch, F Kirchhoff… - Advanced drug delivery …, 2020 - Elsevier
To date, no effective vaccines or therapies are available against the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), the causative pandemic agent of the coronavirus …

Airborne transmission of COVID-19: aerosol dispersion, lung deposition, and virus-receptor interactions

YY Zuo, WE Uspal, T Wei - ACS nano, 2020 - ACS Publications
Coronavirus disease 2019 (COVID-19), due to infection by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is now causing a global pandemic. Aerosol …

Higher infectivity of the SARS‐CoV‐2 new variants is associated with K417N/T, E484K, and N501Y mutants: an insight from structural data

A Khan, T Zia, M Suleman, T Khan… - Journal of cellular …, 2021 - Wiley Online Library
The evolution of the SARS‐CoV‐2 new variants reported to be 70% more contagious than
the earlier one is now spreading fast worldwide. There is an instant need to discover how …

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

A Stukalov, V Girault, V Grass, O Karayel, V Bergant… - Nature, 2021 - nature.com
The emergence and global spread of SARS-CoV-2 has resulted in the urgent need for an in-
depth understanding of molecular functions of viral proteins and their interactions with the …

Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes

LF de Lima, AL Ferreira, MDT Torres… - Proceedings of the …, 2021 - National Acad Sciences
COVID-19 has led to over 3.47 million deaths worldwide and continues to devastate
primarily middle-and low-income countries. High-frequency testing has been proposed as a …

A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection

DA Jamison Jr, S Anand Narayanan… - European Journal of …, 2022 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has claimed approximately 5 million lives
and 257 million cases reported globally. This virus and disease have significantly affected …

SARS-CoV-2 S protein: ACE2 interaction reveals novel allosteric targets

PV Raghuvamsi, NK Tulsian, F Samsudin, X Qian… - Elife, 2021 - elifesciences.org
The Spike (S) protein is the main handle for SARS-CoV-2 to enter host cells via surface
ACE2 receptors. How ACE2 binding activates proteolysis of S protein is unknown. Here …

Overview of neutralizing antibodies and their potential in COVID-19

JJ Morales-Núñez, JF Muñoz-Valle… - Vaccines, 2021 - mdpi.com
The antibody response to respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a
major focus of COVID-19 research due to its clinical relevance and importance in vaccine …

Modelling conformational state dynamics and its role on infection for SARS-CoV-2 Spike protein variants

N Teruel, O Mailhot… - PLoS computational …, 2021 - journals.plos.org
The SARS-CoV-2 Spike protein needs to be in an open-state conformation to interact with
ACE2 to initiate viral entry. We utilise coarse-grained normal mode analysis to model the …

The SARS-CoV-2 B. 1.618 variant slightly alters the spike RBD–ACE2 binding affinity and is an antibody escaping variant: a computational structural perspective

A Khan, J Gui, W Ahmad, I Haq, M Shahid, AA Khan… - RSC …, 2021 - pubs.rsc.org
Continuing reports of new SARS-CoV-2 variants have caused worldwide concern and
created a challenging situation for clinicians. The recently reported variant B. 1.618, which …