Mouse models are a critical tool for studying human diseases, particularly developmental
disorders. However, conventional approaches for phenotyping may fail to detect subtle …

The advent of high-throughput single-cell genomics technologies has fundamentally
transformed biological sciences. Currently, millions of cells from complex biological tissues …

Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …

Hundreds of millions of single cells have been analyzed to date using high throughput
transcriptomic methods, thanks to technological advances driving the increasingly rapid …

Early organogenesis represents a key step in animal development, during which pluripotent
cells diversify to initiate organ formation. Here, we sampled 300,000 single-cell …

Meningiomas, although mostly benign, can be recurrent and fatal. World Health
Organization (WHO) grading of the tumor does not always identify high-risk meningioma …

The mammalian body plan is shaped by rhythmic segmentation of mesoderm into somites,
which are transient embryonic structures that form down each side of the neural tube. We …

James German's work to establish the natural history and cancer risk associated with Bloom
syndrome (BS) has had a strong influence on the generation of scientists and clinicians …

Many single cell RNA-sequencing (scRNA-seq) data analysis workflows rely on methods
that embed and visualize the properties of a k-nearest neighbor (kNN) graph in two …

University of Southern Denmark Integrative analysis of single-cell transcriptomics Møller,
Andreas Fønns Page 1 University of Southern Denmark Integrative analysis of single-cell …