SARS-CoV-2 evolution in the Omicron era

C Roemer, DJ Sheward, R Hisner, F Gueli… - Nature …, 2023 - nature.com
Abstract Since SARS-CoV-2 BA. 5 (Omicron) emerged and spread in 2022, Omicron
lineages have markedly diversified. Here we review the evolutionary trajectories and …

Puzzles, challenges, and information reservoir of SARS-CoV-2 quasispecies

E Domingo, B Martínez-González… - Journal of …, 2023 - Am Soc Microbiol
Upon the emergence of SARS-CoV-2 in the human population, it was conjectured that for
this coronavirus the dynamic intra-host heterogeneity typical of RNA viruses would be toned …

[HTML][HTML] Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants

Q Wang, S Iketani, Z Li, L Liu, Y Guo, Y Huang… - Cell, 2023 - cell.com
The BQ and XBB subvariants of SARS-CoV-2 Omicron are now rapidly expanding, possibly
due to altered antibody evasion properties deriving from their additional spike mutations …

[HTML][HTML] Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Y Cao, F Jian, J Wang, Y Yu, W Song, A Yisimayi… - Nature, 2023 - nature.com
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent …

[HTML][HTML] Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

A Yisimayi, W Song, J Wang, F Jian, Y Yu, X Chen… - Nature, 2024 - nature.com
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19
vaccine compositions. However, immune imprinting induced by vaccination based on the …

[HTML][HTML] ACE2 binding and antibody evasion in enhanced transmissibility of XBB. 1.5

C Yue, W Song, L Wang, F Jian, X Chen… - The Lancet Infectious …, 2023 - thelancet.com
SARS-CoV-2 subvariants BQ. 1.1 and XBB. 1 have been circulating globally with superior
growth advantages over most omicron mutants (appendix p 5). However, XBB. 1.5, a …

[HTML][HTML] Characterization of the enhanced infectivity and antibody evasion of Omicron BA. 2.75

Y Cao, W Song, L Wang, P Liu, C Yue, F Jian, Y Yu… - Cell host & …, 2022 - cell.com
Summary Recently emerged SARS-CoV-2 Omicron subvariant, BA. 2.75, displayed a growth
advantage over circulating BA. 2.38, BA. 2.76, and BA. 5 in India. However, the underlying …

[HTML][HTML] Neutralization, effector function and immune imprinting of Omicron variants

A Addetia, L Piccoli, JB Case, YJ Park, M Beltramello… - Nature, 2023 - nature.com
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …

Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution

W Ma, H Fu, F Jian, Y Cao, M Li - Nature Ecology & Evolution, 2023 - nature.com
Mutations in the SARS-CoV-2 genome could confer resistance to pre-existing antibodies
and/or increased transmissibility. The recently emerged Omicron subvariants exhibit a …

[HTML][HTML] Enhanced transmissibility, infectivity, and immune resistance of the SARS-CoV-2 omicron XBB. 1.5 variant

K Uriu, J Ito, J Zahradnik, S Fujita, Y Kosugi… - The Lancet infectious …, 2023 - thelancet.com
Enhanced transmissibility, infectivity, and immune resistance of the SARS-CoV-2 omicron
XBB.1.5 variant - The Lancet Infectious Diseases Skip to Main Content Advertisement The …