[HTML][HTML] Network-based approaches for modeling disease regulation and progression
Molecular interaction networks lay the foundation for studying how biological functions are
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …
[HTML][HTML] Melatonin: Regulation of viral phase separation and Epitranscriptomics in post-acute sequelae of COVID-19
The relentless, protracted evolution of the SARS-CoV-2 virus imposes tremendous pressure
on herd immunity and demands versatile adaptations by the human host genome to counter …
on herd immunity and demands versatile adaptations by the human host genome to counter …
[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes
D Marakulina, IE Vorontsov, IV Kulakovskiy… - Nucleic Acids …, 2023 - academic.oup.com
We present an update of EpiFactors, a manually curated database providing information
about epigenetic regulators, their complexes, targets, and products which is openly …
about epigenetic regulators, their complexes, targets, and products which is openly …
[HTML][HTML] LINE1-mediated reverse transcription and genomic integration of SARS-CoV-2 mRNA detected in virus-infected but not in viral mRNA-transfected cells
SARS-CoV-2 sequences can be reverse-transcribed and integrated into the genomes of
virus-infected cells by a LINE1-mediated retrotransposition mechanism. Whole-genome …
virus-infected cells by a LINE1-mediated retrotransposition mechanism. Whole-genome …
[HTML][HTML] Involvement of epigenetics in affecting host immunity during SARS-CoV-2 infection
Abstract Coronavirus disease 19 (COVID-19) is caused by a highly contagious RNA virus
Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2), originated in December …
Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2), originated in December …
Unwinding the roles of RNA helicase MOV10
A Nawaz, T Shilikbay, G Skariah… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
MOV10 is an RNA helicase that associates with the RNA‐induced silencing complex
component Argonaute (AGO), likely resolving RNA secondary structures. MOV10 also binds …
component Argonaute (AGO), likely resolving RNA secondary structures. MOV10 also binds …
[HTML][HTML] Implications of RNA viruses in the male reproductive tract: an outlook on SARS-CoV-2
MI Zafar, J Yu, H Li - Frontiers in Microbiology, 2021 - frontiersin.org
Emerging viral infections continuously pose a threat to human wellbeing. Several RNA
viruses have managed to establish access to the male reproductive tract and persist in …
viruses have managed to establish access to the male reproductive tract and persist in …
Epigenetic rewiring of pathways related to odour perception in immune cells exposed to SARS-CoV-2 in vivo and in vitro
ABSTRACT A majority of SARS-CoV-2 recoverees develop only mild-to-moderate
symptoms, while some remain completely asymptomatic. Although viruses, including SARS …
symptoms, while some remain completely asymptomatic. Although viruses, including SARS …
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases
M Rahimi-Tesiye, M Zaersabet, S Salehiyeh… - … et Biophysica Acta (BBA …, 2023 - Elsevier
The tripartite motif (TRIM) family proteins are a group of proteins involved in different
signaling pathways. The changes in the expression regulation, function, and signaling of this …
signaling pathways. The changes in the expression regulation, function, and signaling of this …