[HTML][HTML] Research on ferroptosis as a therapeutic target for the treatment of neurodegenerative diseases

Y Wang, M Lv, W Zhao - Ageing research reviews, 2023 - Elsevier
Ferroptosis is an iron-and lipid peroxidation (LPO)-mediated programmed cell death type.
Recently, mounting evidence has indicated the involvement of ferroptosis in …

The significant mechanism and treatments of cell death in heatstroke

Z Wang, J Zhu, D Zhang, J Lv, L Wu, Z Liu - Apoptosis, 2024 - Springer
With global warming, extreme environmental heat is becoming a social issue of concern,
which can cause adverse health results including heatstroke (HS). Severe heat stress is …

Ambient particulate matter exposure induces ferroptosis in hippocampal cells through the GSK3B/Nrf2/GPX4 pathway

J Gui, L Wang, J Liu, H Luo, D Huang, X Yang… - Free Radical Biology …, 2024 - Elsevier
Epidemiological studies have established a robust correlation between exposure to ambient
particulate matter (PM) and various neurological disorders, with dysregulation of intracellular …

The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway

Y Shao, Y Xu, H Di, X Shi, Y Wang, H Liu… - IET …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disease with high incidence and
widespread attention. There is currently no clear clarification of the pathogenesis. However …

[HTML][HTML] SuanZaoRen decoction alleviates neuronal loss, synaptic damage and ferroptosis of AD via activating DJ-1/Nrf2 signaling pathway

Q Long, T Li, Q Zhu, L He, B Zhao - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance SuanZaoRen Decoction (SZRD), a famous herbal
prescription, and has been widely proven to have positive therapeutic effects on insomnia …

[HTML][HTML] Nlrp6 protects from corticosterone-induced NSPC ferroptosis by modulating RIG-1/MAVS-mediated mitophagy

J Shen, P Xie, J Wang, F Yang, S Li, H Jiang, X Wu… - Redox Biology, 2024 - Elsevier
Hippocampal neural stem/progenitor cells (NSPCs) are highly vulnerable to different stress
stimuli, resulting in adult neurogenesis decline and eventual cognitive defects. Our previous …

Machine learning identification and immune infiltration of disulfidptosis‐related Alzheimer's disease molecular subtypes

Y Zhu, L Kong, T Han, Q Yan… - Immunity, Inflammation and …, 2023 - Wiley Online Library
Background Alzheimer's disease (AD) is a common neurodegenerative disorder.
Disulfidptosis is a newly discovered form of programmed cell death that holds promise as a …

[HTML][HTML] Exo-miR-144-3p as a promising diagnostic biomarker for depressive symptoms in heart failure

R Wang, K Huang, Y Feng, J Duan, H Ying, Q Shi… - Neurobiology of …, 2024 - Elsevier
Abstracts Aims The prevalence of depression is higher in heart failure (HF) patients. Early
screening of depressive symptoms in HF patients and timely intervention can help to …

Exploring causal effects of gut microbiota and metabolites on body fat percentage using two‐sample Mendelian randomization

X Wang, C Lu, X Li, P Ye, J Ma… - Diabetes, Obesity and …, 2024 - Wiley Online Library
Aim The relationship between the gut microbiota, metabolites and body fat percentage (BFP)
remains unexplored. We systematically assessed the causal relationships between gut …

Identification and prediction of m7G-related Alzheimer's disease subtypes: insights from immune infiltration and machine learning models

C Ma, J Li, Y Chi, X Sun, M Yang, X Sui - Frontiers in Aging …, 2023 - frontiersin.org
Introduction Alzheimer's disease (AD) is a complex and progressive neurodegenerative
disorder that primarily affects older individuals. N7-methylguanosine (m7G) is a common …