[HTML][HTML] Autophagy and longevity: Evolutionary hints from hyper-longevous mammals

AG Locatelli, S Cenci - Frontiers in Endocrinology, 2022 - frontiersin.org
Autophagy is a fundamental multi-tasking adaptive cellular degradation and recycling
strategy. Following its causal implication in age-related decline, autophagy is currently …

Epigenetics and island‐mainland divergence in an insectivorous small mammal

ML Cossette, DT Stewart, A Haghani… - Molecular …, 2023 - Wiley Online Library
Geographically isolated populations, specifically island‐mainland counterparts, tend to
exhibit phenotypic variation in many species. The so‐called island syndrome occurs when …

[PDF][PDF] Comparative analysis reveals epigenomic evolution related to species traits and genomic imprinting in mammals

Y Hu, S Yuan, X Du, J Liu, W Zhou, F Wei - The Innovation, 2023 - cell.com
DNA methylation is an epigenetic modification that plays a crucial role in various regulatory
processes, including gene expression regulation, transposable element repression, and …

Long-term field studies in bat research: importance for basic and applied research questions in animal behavior

G Kerth - Behavioral Ecology and Sociobiology, 2022 - Springer
Animal species differ considerably in longevity. Among mammals, short-lived species such
as shrews have a maximum lifespan of about a year, whereas long-lived species such as …

DNA methylation networks underlying mammalian traits

A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu… - Science, 2023 - science.org
Using DNA methylation profiles (n= 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …

An evaluation of aging measures: from biomarkers to clocks

Q Wang, T Hou, Q Wang, J He, L Wang, J Si, S Chen - Biogerontology, 2023 - Springer
With the increasing number of aged population and growing burden of healthy aging
demands, a rational standard for evaluation aging is in urgent need. The advancement of …

Phylogeographic aspects of bat lyssaviruses in Europe: A review

H Dundarova, N Ivanova-Aleksandrova, S Bednarikova… - Pathogens, 2023 - mdpi.com
During the last few decades, bat lyssaviruses have become the topic of intensive molecular
and epidemiological investigations. Since ancient times, rhabdoviruses have caused fatal …

Bats experience age-related hearing loss (presbycusis)

YC Tarnovsky, S Taiber, Y Nissan… - Life Science …, 2023 - life-science-alliance.org
Hearing loss is a hallmark of aging, typically initially affecting the higher frequencies. In
echolocating bats, the ability to discern high frequencies is essential. However, nothing is …

Oxidative damage varies in response to bacterial, fungal and viral antigen challenges in bats

D Costantini, J Schad, GÁ Czirják… - Journal of …, 2023 - journals.biologists.com
The immune system plays an important role in defending against pathogens and regulating
physiological homeostasis, but the strength of the immune responses depends on the type …

Next generation sequencing revolutionizes organismal biology research in bats

KM Garg, V Lamba, A Sanyal, P Dovih… - Journal of Molecular …, 2023 - Springer
The advent of next generation sequencing technologies (NGS) has greatly accelerated our
understanding of critical aspects of organismal biology from non-model organisms. Bats …