Physical and cognitive performances change across lifespan. Studying cohorts of
individuals in specific age ranges and athletic abilities remains essential in assessing the …

Understanding and facilitating healthy aging has become a major goal in medical research
and it is becoming increasingly acknowledged that there is a need for understanding the …

Numerous genetic manipulations that extend lifespan in mice have been discovered over
the past two decades, the most robust of which has arguably been the down regulation of …

This chapter covers the state-of-the-art multivariate statistical methods designed for high
dimensional multiset omics data analysis. Recent biotechnological developments have …

The greatest significant influence on human life span and health is inevitable ageing. One of
the distinguishing characteristics of ageing is the gradual decrease of muscle mass and …

Developing a workflow for metabolite profiling from biological fluids using mass
spectrometry is imperative to extract accurate information. In this study, urine samples from …

This study identified microRNAs involved in myocardial infarction (MI) through a novel
system-level approach using RNA sequencing data in an MI mouse model. This approach …

The kidneys are metabolically active organs with importance in several physiological tasks
such as the secretion of soluble wastes into the urine and synthesizing glucose and …

Circadian clock function declines with ageing, which can aggravate ageing‐related
diseases such as type 2 diabetes and neurodegenerative disorders. Understanding age …

Aim Inflammatory biomarkers are associated with aging and disease-specific outcomes. We
propose neutrophil–lymphocyte ratio (NLR) informs survival in a noncancer-bearing …