Many scientific studies, especially in the biomedical sciences, generate data measured
simultaneously over a multitude of units, over a period of time, and under different conditions …

Frailty is a common geriatric syndrome and a risk factor for many diseases, even mortality.
However, the specific molecular biomarkers for diagnosis and therapeutic targets of frailty …

Understanding and facilitating healthy aging has become a major goal in medical research
and it is becoming increasingly acknowledged that there is a need for understanding the …

Abstract In a 2020 paper, 37 authors, all researchers and students in aging biology, pointed
out a general lack of consensus in their field,“even on the most fundamental questions” …

Highlights•Aging and diet impact phenotypic flexibility as assessed by challenge
tests.•Plasma metabolites are poor predictors of muscle metabolism during aging.•Age …

Metabolomics is an emerging approach in the realm of omics. Despite its rapid emergence
two decades ago, it has already proven an impressive potential in improving traits related to …

The review highlights various methods for deciphering the nucleotide sequence
(sequencing) of nucleic acids and their importance for the implementation of the three main …

There is increasing evidence that many molecular processes exhibit differences with age 1
and sex. Such differences produces also differences in the insurgence and progression of …

Background: Aging, especially its related immune senescence, is an important risk factor for
many diseases, including neurodegenerative diseases, cardiovascular diseases and …

Alzheimer's disease (AD) and AD-related dementias (ADRD) are complex multifactorial
processes where epigenetic and biochemical changes occur many years before the onset of …