Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

The restriction of calories, branched-chain amino acids, and methionine have all been
shown to extend lifespan in model organisms. Recently, glycine was shown to significantly …

Epigenetic clocks were initially developed to track chronological age, but accumulating
evidence indicates that they can also predict biological age. They are usually based on the …

The strong interest shown in the study of the causes of aging in recent decades has
uncovered many mechanisms that could contribute to the rate of aging. These include …

The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an
important component of the human body that helps maintain tissue architecture and cellular …

Aging is characterised by the progressive accumulation of cellular dysfunction, stress, and
inflammation. A large body of evidence implicates mitochondrial dysfunction as a cause or …

The pursuit for the fountain of youth has long been a fascination amongst scientists and
humanity. Ageing is broadly characterized by a cellular decline with increased susceptibility …

Epigenetic aging clocks are computational models that predict age using DNA methylation
information. Initially, first-generation clocks were developed to make predictions using CpGs …

Objective The aim of the study is to examine associations between years of firefighting
service and eight chronological age-adjusted measures of blood leukocyte epigenetic age …

Ageing is a natural ontogenetic phenomenon that entails a decrease in the adaptive
capacity of the organism, as a result of which the body becomes less adaptable to stressful …