Biomarkers of aging would give the true “biological age”, which may be different from the
chronological age. Population perspectives regarding to aging, age-related diseases and …

Recently, circular RNAs (circRNAs) have been revealed to be an important non-coding
element of the transcriptome. The brain contains the most abundant and widespread …

Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly
heritable, but no genetic variants have been consistently identified. We aimed to identify …

The contribution of individual genetic determinants of aging to the adverse clinical outcomes
and altered inflammation mediator networks characteristic of aged trauma patients is …

Limited lifespan and senescence are near-universal phenomena. These quantitative traits
exhibit variation in natural populations due to the segregation of many interacting loci and …

Women are living longer than men and it seems that one of the reasons could be better
immune system of females. In Poland, contrary to many European countries, women retire …

Evidence from model organisms suggests that the insulin/IGF-1 signaling pathway has an
important, evolutionarily conserved influence over rate of aging and thus longevity. In …

Background: Longevity is considered the result of interactions between environmental and
genetic factors. Aim: To investigate the possible association of body mass index and the …

In eukaryotes, numerous genetic factors contribute to the lifespan including metabolic
enzymes, signal transducers, and transcription factors. As previously reported, the forkhead …

The role of superoxide dismutases (SODs) in aging and oxidative stress regulation has been
widely studied and there is growing evidence that imbalances in these processes influence …