Origins of pathological myofibroblasts in lung fibrosis: insights from lineage tracing mouse models in the single-cell RNA sequencing era

M Homps-Legrand, B Crestani… - American Journal of …, 2023 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a rare interstitial lung disease with a poor prognosis.
Chronic microinjuries, mainly caused by environmental factors to an aging alveolar …

High-fat diet related lung fibrosis-epigenetic regulation matters

J Yang, C Liang, L Liu, L Wang, G Yu - Biomolecules, 2023 - mdpi.com
Pulmonary fibrosis (PF) is an interstitial lung disease characterized by the destruction of the
pulmonary parenchyma caused by excessive extracellular matrix deposition. Despite the …

Modeling fibrotic alveolar transitional cells with pluripotent stem cell-derived alveolar organoids

V Ptasinski, SJ Monkley, K Öst, M Tammia… - Life science …, 2023 - life-science-alliance.org
Repeated injury of the lung epithelium is proposed to be the main driver of idiopathic
pulmonary fibrosis (IPF). However, available therapies do not specifically target the …

[HTML][HTML] Short histological kaleidoscope–recent findings in histology. Part III

AM Constantin, CM Mihu, AB Boşca… - Romanian Journal of …, 2023 - ncbi.nlm.nih.gov
The paper provides an overview of the current understanding of different cells' biology (eg,
keratinocytes, Paneth cells, myoepithelial cells, myofibroblasts, chondroclasts, monocytes …

A genome–wide CRISPR activation screen identifies SCREEM a novel SNAI1 super-enhancer demarcated by eRNAs

DB Uthaya Kumar, M Yurieva, J Grassmann… - Frontiers in Molecular …, 2023 - frontiersin.org
The genome is pervasively transcribed to produce a vast array of non-coding RNAs
(ncRNAs). Long non-coding RNAs (lncRNAs) are transcripts of> 200 nucleotides and are …

[PDF][PDF] Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis

V Ptasinski - 2023 - portal.research.lu.se
The lung is a vital organ in the body enabling us to breathe. During chronic lung diseases,
the function of the lung is impacted by damage to the tissue structure. Idiopathic pulmonary …

[引用][C] High-Fat Diet Related Lung Fibrosis-Epigenetic Regulation Matters. Biomolecules 2023, 13, 558

J Yang, C Liang, L Liu, L Wang, G Yu - 2023 - europepmc.org
Pulmonary fibrosis (PF) is an interstitial lung disease characterized by the destruction of the
pulmonary parenchyma caused by excessive extracellular matrix deposition. Despite the …