Resveratrol as sensitizer in colorectal cancer plasticity

A Brockmueller, A Sajeev, L Koklesova… - Cancer and Metastasis …, 2024 - Springer
Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …

The synergistic effects of polyphenols and intestinal microbiota on osteoporosis

K Wang, S Hu - Frontiers in Immunology, 2023 - frontiersin.org
Osteoporosis is a common metabolic disease in middle-aged and elderly people. It is
characterized by a reduction in bone mass, compromised bone microstructure, heightened …

Neuromodulatory effect of vardenafil on aluminium chloride/d-galactose induced Alzheimer's disease in rats: emphasis on amyloid-beta, p-tau, PI3K/Akt/p53 pathway …

HH Awad, MA Desouky, A Zidan, M Bassem… - …, 2023 - Springer
Dysregulation of protein homeostasis, proteostasis, is a distinctive hallmark of many
neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant …

Expected and unexpected effects of pharmacological antioxidants

I Tyuryaeva, O Lyublinskaya - International Journal of Molecular Sciences, 2023 - mdpi.com
In this review, we have collected the existing data on the bioactivity of antioxidants (N-
acetylcysteine, polyphenols, vitamin C) which are traditionally used in experimental biology …

Resveratrol modulates the inflammatory response in hPDLSCs via the NRF2/HO‐1 and NF‐κB pathways and promotes osteogenic differentiation

Y Ma, Y Qian, Y Chen, X Ruan, X Peng… - Journal of …, 2024 - Wiley Online Library
Objective The purpose of this study was to investigate resveratrol's specific role as an anti‐
inflammatory and osteogenic differentiation of hPDLSCs in periodontitis and to reveal the …

Natural Products as Dietary Agents for the Prevention and Mitigation of Oxidative Damage and Inflammation in the Intestinal Barrier

C Martins-Gomes, FM Nunes, AM Silva - Antioxidants, 2024 - mdpi.com
Food intake is a basic need to sustain life, but foodborne pathogens and food-related
xenobiotics are also the main health concerns regarding intestinal barrier homeostasis. With …

Researching new drug combinations with senolytic activity using senescent human lung fibroblasts MRC-5 cell line

MCX de Godoy, JA Macedo, A Gambero - Pharmaceuticals, 2024 - mdpi.com
Therapeutically targeting senescent cells seems to be an interesting perspective in treating
chronic lung diseases, which are often associated with human aging. The combination of the …

[HTML][HTML] T-2 toxin-induced testicular impairment by triggering oxidative stress and ferroptosis

J He, H Jin, J Guo, K Li, L Jia, Y Li, L Zhang - … and Environmental Safety, 2024 - Elsevier
T-2 toxin is a trichothecene mycotoxin of significant danger to humans and animals. Its
impact on reproductive toxicity is attributed to oxidative stress, which ultimately leads to cell …

Remediation Strategies for Mycotoxins in Animal Feed

J Deng, JC Huang, ZJ Xu, Y Liu, NA Karrow, M Liu… - Toxins, 2023 - mdpi.com
Mycotoxins occur widely in various animal feedstuffs, with more than 500 mycotoxins
identified so far [1]. Generally, aflatoxin B1 (AFB1), zearalenone (ZEN), deoxynivalenol …

Resveratrol can improve spinal cord injury by activating Nrf2/HO-1 signaling pathway

S Tang, BOA Botchway, Y Zhang, X Wang… - Annals of Anatomy …, 2024 - Elsevier
Spinal cord injury (SCI) often induces severe sensory and motor dysfunction. Oxidative
stress is an important pathophysiological process of secondary SCI, and its inhibition could …