The pursuit for the fountain of youth has long been a fascination amongst scientists and
humanity. Ageing is broadly characterized by a cellular decline with increased susceptibility …

Aging is a complex progression of changes best characterized as the chronic dysregulation
of cellular processes leading to deteriorated tissue and organ function. Although aging …

The present perspective article proposes an etiopathological model for multiple sclerosis
pathogenesis and progression associated with the activation of human endogenous …

Glaucoma, a chronic neurodegenerative disease, is a leading cause of age-related
blindness worldwide and characterized by the progressive loss of retinal ganglion cells …

A mechanistic connection between aging and development is largely unexplored. Through
profiling age-related chromatin and transcriptional changes across 22 murine cell types …

In aging, the organism is unable to counteract certain harmful influences over its lifetime
which leads to progressive dysfunction and eventually death, thus delineating aging as one …

A wealth of evidence has emerged that there is an association between aging, senescence
and tumorigenesis. Senescence, a biological process by which cells cease to divide and …

Aging populations worldwide are placing age-related diseases at the forefront of the
research agenda. The therapeutic potential of natural substances, especially propolis and its …

Lifespan is a complex quantitative trait involving genetic and non-genetic factors as well as
the peculiarities of ontogenesis. As with all quantitative traits, lifespan shows considerable …

Aging causes numerous age-related diseases, leading the human species to death.
Nevertheless, rejuvenating strategies based on cell epigenetic modifications are a possible …