Targeting the gut microbiota for cancer therapy

MR Fernandes, P Aggarwal, RGF Costa… - Nature Reviews …, 2022 - nature.com
Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

Gut microbiome immaturity and childhood acute lymphoblastic leukaemia

I Peppas, AM Ford, CL Furness, MF Greaves - Nature Reviews Cancer, 2023 - nature.com
Acute lymphoblastic leukaemia (ALL) is the most common cancer of childhood. Here, we
map emerging evidence suggesting that children with ALL at the time of diagnosis may have …

Gut-brain pathogenesis of post-acute COVID-19 neurocognitive symptoms

AM Plummer, YL Matos, HC Lin, SG Ryman… - Frontiers in …, 2023 - frontiersin.org
Approximately one third of non-hospitalized coronavirus disease of 2019 (COVID-19)
patients report chronic symptoms after recovering from the acute stage of severe acute …

The role of rumen microbiota and its metabolites in subacute ruminal acidosis (SARA)-induced inflammatory diseases of ruminants

Y Fu, Y He, K Xiang, C Zhao, Z He, M Qiu, X Hu… - Microorganisms, 2022 - mdpi.com
Subacute ruminal acidosis (SARA) is a common metabolic disease in ruminants. In the early
stage of SARA, ruminants do not exhibit obvious clinical symptoms. However, SARA often …

Interaction between microbiota and immunity and its implication in colorectal cancer

C Xing, Y Du, T Duan, K Nim, J Chu, HY Wang… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world.
Besides genetic causes, colonic inflammation is one of the major risk factors for CRC …

Gut Bacteroides act in a microbial consortium to cause susceptibility to severe malaria

RK Mandal, A Mandal, JE Denny, R Namazii… - Nature …, 2023 - nature.com
Malaria is caused by Plasmodium species and remains a significant cause of morbidity and
mortality globally. Gut bacteria can influence the severity of malaria, but the contribution of …

Short-chain fatty acids in the microbiota–gut–brain axis: role in neurodegenerative disorders and viral infections

A Majumdar, IP Siva Venkatesh… - ACS Chemical …, 2023 - ACS Publications
The gut–brain axis (GBA) is the umbrella term to include all bidirectional communication
between the brain and gastrointestinal (GI) tract in the mammalian body. Evidence from over …

Possible therapeutic mechanisms and future perspectives of vaginal microbiota transplantation

M Tuniyazi, N Zhang - Microorganisms, 2023 - mdpi.com
Microbial communities inhabiting the human body play a crucial role in protecting the host
against pathogens and inflammation. Disruptions to the microbial composition can lead to …

[HTML][HTML] Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections

C Feng, C Jin, K Liu, Z Yang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Microbiota-derived short-chain fatty acids (SCFAs) are crucial for protecting the intestinal
barrier and regulating the immune response during infections. Recent studies show that viral …

The gut–liver axis in pediatric liver health and disease

SL Rager, MY Zeng - Microorganisms, 2023 - mdpi.com
There has been growing interest in the complex host–microbe interactions within the human
gut and the role these interactions play in systemic health and disease. As an essential …