Epigenetic age prediction
DJ Simpson, T Chandra - Aging cell, 2021 - Wiley Online Library
Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …
[HTML][HTML] How old is my dog? Identification of rational age groupings in pet dogs based upon normative age-linked processes
ND Harvey - Frontiers in veterinary science, 2021 - frontiersin.org
Behavioral development is a lifelong process where cognitive traits such as learning and
memory may be expected to take quadratic or linear trajectories. It is common practice for …
memory may be expected to take quadratic or linear trajectories. It is common practice for …
DNA methylation predicts age and provides insight into exceptional longevity of bats
Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …
DNA methylation clocks for dogs and humans
DNA methylation profiles have been used to develop biomarkers of aging known as
epigenetic clocks, which predict chronological age with remarkable accuracy and show …
epigenetic clocks, which predict chronological age with remarkable accuracy and show …
Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging
Numerous studies have shown that epigenetic age—an individual's degree of aging based
on patterns of DNA methylation—can be computed and is associated with an array of factors …
on patterns of DNA methylation—can be computed and is associated with an array of factors …
Hibernation slows epigenetic ageing in yellow-bellied marmots
Species that hibernate generally live longer than would be expected based solely on their
body size. Hibernation is characterized by long periods of metabolic suppression (torpor) …
body size. Hibernation is characterized by long periods of metabolic suppression (torpor) …
The rate of epigenetic drift scales with maximum lifespan across mammals
EM Bertucci-Richter, BB Parrott - Nature Communications, 2023 - nature.com
Epigenetic drift or “disorder” increases across the mouse lifespan and is suggested to
underlie epigenetic clock signals. While the role of epigenetic drift in determining maximum …
underlie epigenetic clock signals. While the role of epigenetic drift in determining maximum …
Genetic and epigenetic dependencies in colorectal cancer development
S Parmar, H Easwaran - Gastroenterology Report, 2022 - academic.oup.com
Recent studies have mapped key genetic changes in colorectal cancer (CRC) that impact
important pathways contributing to the multistep models for CRC initiation and development …
important pathways contributing to the multistep models for CRC initiation and development …
Epigenetic clock and methylation studies in cats
Human DNA methylation profiles have been used successfully to develop highly accurate
biomarkers of aging (“epigenetic clocks”). Although these human epigenetic clocks are not …
biomarkers of aging (“epigenetic clocks”). Although these human epigenetic clocks are not …
DNA methylation as a tool to explore ageing in wild roe deer populations
DNA methylation‐based biomarkers of ageing (epigenetic clocks) promise to lead to new
insights into evolutionary biology of ageing. Relatively little is known about how the natural …
insights into evolutionary biology of ageing. Relatively little is known about how the natural …