A review of the biological role of miRNAs in prostate cancer suppression and progression

AS Doghish, A Ismail, HA El-Mahdy, MA Elkady… - International journal of …, 2022 - Elsevier
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application

M Li, L Li, J Zheng, Z Li, S Li, K Wang, X Chen - Molecular Cancer, 2023 - Springer
Renal cell carcinoma (RCC) is a major pathological type of kidney cancer and is one of the
most common malignancies worldwide. The unremarkable symptoms of early stages …

Nanoarchitectonics-assisted simultaneous fluorescence detection of urinary dual miRNAs for noninvasive diagnosis of prostate cancer

P Jiang, Y Bai, L Yan, P Feng, K Huang… - Analytical …, 2023 - ACS Publications
Herein, we report a fluorescence strategy for the homogeneous and simultaneous analysis
of urine miRNA-375 and miRNA-148a. The target miRNAs in urine bonded the devised …

Cellular and molecular mechanisms associating obesity to bone loss

YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes

M Wang, K Xie, S Zhao, N Jia, Y Zong, W Gu, Y Cai - Molecular Medicine, 2023 - Springer
Background It has been documented that aerobic exercise (AE) has a positive effect on
improving cognitive function in type 2 diabetes (T2DM) patients. Here, we tried to explore …

A three-stage eccDNA based molecular profiling significantly improves the identification, prognosis assessment and recurrence prediction accuracy in patients with …

Z Li, B Wang, H Liang, Y Li, Z Zhang, L Han - Cancer Letters, 2023 - Elsevier
Glioblastoma (GBM) progression is influenced by intratumoral heterogeneity. Emerging
evidence has emphasized the pivotal role of extrachromosomal circular DNA (eccDNA) in …

From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer

E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …

Exosomal circRNAs: Novel biomarkers and therapeutic targets for urinary tumors

Q Liu, S Li - Cancer Letters, 2024 - Elsevier
Exosomal circRNAs have emerged as promising biomarkers and therapeutic targets for
urinary tumors. In this review, we explored the intricate role of exosomal circRNAs in …

Nurturing the marriages of urinary liquid biopsies and nano‐diagnostics for precision urinalysis of prostate cancer

C Liao, Z Wu, C Lin, X Chen, Y Zou, W Zhao… - Smart …, 2023 - Wiley Online Library
Prostate cancer remains the second‐most common cancer diagnosed in men, despite the
increasingly widespread use of serum prostate‐specific antigen (PSA) screening. The …

New techniques to identify the tissue of origin for cancer of unknown primary in the era of precision medicine: progress and challenges

W Ma, H Wu, Y Chen, H Xu, J Jiang, B Du… - Briefings in …, 2024 - academic.oup.com
Despite a standardized diagnostic examination, cancer of unknown primary (CUP) is a rare
metastatic malignancy with an unidentified tissue of origin (TOO). Patients diagnosed with …