[HTML][HTML] Molecular biomarkers in cancer

VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Colon cancer transcriptome

K Mokhtari, M Peymani, M Rashidi… - Progress in biophysics …, 2023 - Elsevier
Over the last four decades, methodological innovations have continuously changed
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …

[HTML][HTML] Characterization of Wnt signaling pathway under treatment of Lactobacillus acidophilus postbiotic in colorectal cancer using an integrated in silico and in vitro …

N Erfanian, S Nasseri, A Miraki Feriz, H Safarpour… - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) is a prevalent and life-threatening cancer closely associated with
the gut microbiota. Probiotics, as a vital microbiota group, interact with the host's colonic …

[HTML][HTML] Colorectal cancer: current updates and future perspectives

R Marcellinaro, D Spoletini, M Grieco, P Avella… - Journal of Clinical …, 2023 - mdpi.com
Colorectal cancer is a frequent neoplasm in western countries, mainly due to dietary and
behavioral factors. Its incidence is growing in developing countries for the westernization of …

[HTML][HTML] Transient loss of Polycomb components induces an epigenetic cancer fate

V Parreno, V Loubiere, B Schuettengruber, L Fritsch… - Nature, 2024 - nature.com
Although cancer initiation and progression are generally associated with the accumulation
of somatic mutations,, substantial epigenomic alterations underlie many aspects of …

[HTML][HTML] Spectrum of BRAF aberrations and its potential clinical implications: insights from integrative pan-cancer analysis

Q Yi, J Peng, Z Xu, Q Liang, Y Cai, B Peng… - … in Bioengineering and …, 2022 - frontiersin.org
B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is frequently altered in
multiple cancer types, and BRAF V600 mutations act as a prime target for precision therapy …

[HTML][HTML] A multi-omics overview of colorectal cancer to address mechanisms of disease, metastasis, patient disparities and outcomes

G Yang, X Yu, DJ Weisenberger, T Lu, G Liang - Cancers, 2023 - mdpi.com
Simple Summary Human colorectal cancer (CRC) is a global health burden, most notably for
minority populations. While screening tools have helped improve disease detection and …

[HTML][HTML] DNA methylation signatures of response to conventional synthetic and biologic disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis

SS Wang, MJ Lewis, C Pitzalis - Biomedicines, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a complex condition that displays heterogeneity in disease
severity and response to standard treatments between patients. Failure rates for …

Unveiling the genetic and epigenetic landscape of colorectal cancer: new insights into pathogenic pathways

H Postwala, Y Shah, PS Parekh, MR Chorawala - Medical Oncology, 2023 - Springer
Colorectal cancer (CRC) is a complex disease characterized by genetic and epigenetic
alterations, playing a crucial role in its development and progression. This review aims to …

[HTML][HTML] Plasma cell-free tumor methylome as a biomarker in solid tumors: biology and applications

DB Sacdalan, S Ul Haq, BH Lok - Current Oncology, 2024 - mdpi.com
DNA methylation is a fundamental mechanism of epigenetic control in cells and its
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …