[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

[HTML][HTML] Aerosol transmission of SARS-CoV-2? Evidence, prevention and control

S Tang, Y Mao, RM Jones, Q Tan, JS Ji, N Li… - Environment …, 2020 - Elsevier
As public health teams respond to the pandemic of coronavirus disease 2019 (COVID-19),
containment and understanding of the modes of severe acute respiratory syndrome …

[HTML][HTML] Inflammasome activation in infected macrophages drives COVID-19 pathology

E Sefik, R Qu, C Junqueira, E Kaffe, H Mirza, J Zhao… - Nature, 2022 - nature.com
Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine
production, viral RNA and a sustained interferon (IFN) response, all of which are …

[PDF][PDF] Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection

A Natarajan, S Zlitni, EF Brooks, SE Vance, A Dahlen… - Med, 2022 - cell.com
Background COVID-19 manifests with respiratory, systemic, and gastrointestinal (GI)
symptoms. 1, SARS-CoV-2 RNA is detected in respiratory and fecal samples, and recent …

[HTML][HTML] Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization

Y Wu, X Cheng, G Jiang, H Tang, S Ming… - npj Biofilms and …, 2021 - nature.com
The human oral and gut commensal microbes play vital roles in the development and
maintenance of immune homeostasis, while its association with susceptibility and severity of …

[HTML][HTML] COVID-19-associated gastrointestinal and liver injury: clinical features and potential mechanisms

P Zhong, J Xu, D Yang, Y Shen, L Wang… - Signal transduction and …, 2020 - nature.com
Abstract Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The infection is spreading globally and poses a …

[HTML][HTML] A humanized mouse model of chronic COVID-19

E Sefik, B Israelow, H Mirza, J Zhao, R Qu, E Kaffe… - Nature …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease that can present as
an uncontrolled, hyperactive immune response, causing severe immunological injury …

The duration of infectiousness of individuals infected with SARS-CoV-2

KA Walsh, S Spillane, L Comber, K Cardwell… - Journal of Infection, 2020 - Elsevier
Objectives To summarise the evidence on the duration of infectiousness of individuals in
whom SARS-CoV-2 ribonucleic acid is detected. Methods A rapid review was undertaken in …

SARS-CoV-2 and other pathogens in municipal wastewater, landfill leachate, and solid waste: A review about virus surveillance, infectivity, and inactivation

U Anand, X Li, K Sunita, S Lokhandwala… - Environmental …, 2022 - Elsevier
This review discusses the techniques available for detecting and inactivating of pathogens
in municipal wastewater, landfill leachate, and solid waste. In view of the current COVID-19 …

Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols

PZ Chen, N Bobrovitz, Z Premji, M Koopmans… - Elife, 2021 - elifesciences.org
Background: Which virological factors mediate overdispersion in the transmissibility of
emerging viruses remains a long-standing question in infectious disease epidemiology …