Current Insights into Tissue Injury of Giant Cell Arteritis: From Acute Inflammatory Responses towards Inappropriate Tissue Remodeling

DA Palamidas, L Chatzis, M Papadaki, I Gissis… - Cells, 2024 - mdpi.com
Giant cell arteritis (GCA) is an autoimmune disease affecting large vessels in patients over
50 years old. It is an exemplary model of a classic inflammatory disorder with IL-6 playing …

Helicobacter pylori Eradication Reverses DNA Damage Response Pathway but Not Senescence in Human Gastric Epithelium

P Kalisperati, E Spanou, IS Pateras… - International Journal of …, 2024 - mdpi.com
Helicobacter pylori (H. pylori) infection induces DNA Double-Strand Breaks (DSBs) and
consequently activates the DNA Damage Response pathway (DDR) and senescence in …

Imaging techniques: essential tools for the study of SARS-CoV-2 infection

A Deroubaix, A Kramvis - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
The world has seen the emergence of a new virus in 2019, SARS-CoV-2, causing the
COVID-19 pandemic and millions of deaths worldwide. Microscopy can be much more …

Bulk and Single-Cell RNA Sequencing Elucidate the Etiology of Severe COVID-19

Ł Huminiecki - International Journal of Molecular Sciences, 2024 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a type of pneumonia caused by the SARS-CoV-2
coronavirus. It can cause acute pulmonary and systemic inflammation, which can lead to …

Loss of CFTR Reverses Senescence Hallmarks in SARS-CoV-2 Infected Bronchial Epithelial Cells

F Merigo, A Lagni, F Boschi, P Bernardi… - International Journal of …, 2024 - mdpi.com
SARS-CoV-2 infection has been recently shown to induce cellular senescence in vivo. A
senescence-like phenotype has been reported in cystic fibrosis (CF) cellular models. Since …

[HTML][HTML] Distinct molecular mechanisms characterizing pathogenesis of SARS-CoV-2

SJ Lee, YJ Kim, DG Ahn - Journal of Microbiology and …, 2022 - ncbi.nlm.nih.gov
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
continued for over 2 years, following the outbreak of coronavirus-19 (COVID-19) in 2019. It …

Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53

JD Lee, BL Menasche, M Mavrikaki, MM Uyemura… - Cell reports, 2023 - cell.com
Summary Coronavirus disease 2019 (COVID-19) remains a significant public health threat
due to the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants …

Radiotherapy for non-cancer diseases: benefits and long-term risks

J Thariat, MP Little, LB Zablotska… - … Journal of Radiation …, 2024 - Taylor & Francis
Purpose The discovery of X-rays was followed by a variety of attempts to treat infectious
diseases and various other non-cancer diseases with ionizing radiation, in addition to …

Convergence of inflammatory response: Salivary cytokine dynamics in coronavirus disease 2019 and periodontal disease

S Gupta, R Mohindra, M Ramola, P Kanta… - Journal of Indian …, 2024 - journals.lww.com
Background: Periodontal disease is associated with immune dysregulation, and cytokines
released can add on to the coronavirus disease 2019 (COVID-19)-associated cytokine …

Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2 Nucleocapsid Protein and Lipofuscin Accumulation in Tissues

R Lira, C Luna-Rivero, FV Morales-Bolaños… - Heliyon, 2024 - cell.com
Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2
Nucleocapsid Protein and Lipofuscin Accumulation in Tissues: Heliyon Skip to Main …