Respiratory syncytial virus infection and novel interventions

AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …

The role of IgG Fc receptors in antibody-dependent enhancement

S Bournazos, A Gupta, JV Ravetch - Nature Reviews Immunology, 2020 - nature.com
Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of
certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non …

Antimicrobial host defence peptides: functions and clinical potential

N Mookherjee, MA Anderson, HP Haagsman… - Nature reviews Drug …, 2020 - nature.com
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19

LA Vella, JR Giles, AE Baxter, DA Oldridge… - Science …, 2021 - science.org
Pediatric coronavirus disease 2019 (COVID-19) after SARS-CoV-2 infection is associated
with fewer hospitalizations and often milder disease than in adults. A subset of children …

Understanding development of malnutrition in hemodialysis patients: a narrative review

S Sahathevan, BH Khor, HM Ng, AH Abdul Gafor… - Nutrients, 2020 - mdpi.com
Hemodialysis (HD) majorly represents the global treatment option for patients with chronic
kidney disease stage 5, and, despite advances in dialysis technology, these patients face a …

Neutrophilic inflammation in asthma and association with disease severity

A Ray, JK Kolls - Trends in immunology, 2017 - cell.com
Asthma is a chronic inflammatory disorder of the airways. While the local infiltration of
eosinophils and mast cells, and their role in the disease have long been recognized …

During the COVID‐19 pandemic where has respiratory syncytial virus gone?

G Di Mattia, R Nenna, E Mancino, V Rizzo… - Pediatric …, 2021 - Wiley Online Library
The diffusion of the SARS‐CoV‐2 virus and the implementation of restrictive measures led to
a drastic reduction of respiratory syncytial virus (RSV) diffusion. Few RSV cases have been …

Melatonin potentials against viral infections including COVID-19: Current evidence and new findings

KB Juybari, MH Pourhanifeh, A Hosseinzadeh… - Virus research, 2020 - Elsevier
Viral infections are dangerous diseases for human health worldwide, which lead to
significant morbidity and mortality each year. Because of their importance and the lack of …

The role of vaccines in preventing bacterial antimicrobial resistance

KU Jansen, C Knirsch, AS Anderson - Nature medicine, 2018 - nature.com
Antimicrobial resistance (AMR) and the associated morbidity and mortality due to bacterial
pathogens have been increasing globally to alarming levels. The World Health Organization …

[HTML][HTML] Neutrophils in respiratory viral infections

C Johansson, FCM Kirsebom - Mucosal immunology, 2021 - Elsevier
Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …