[HTML][HTML] Short-and intermediate-term exposure to ambient fine particulate elements and leukocyte epigenome-wide DNA methylation in older men: the Normative …
Background Several epigenome-wide association studies (EWAS) of ambient particulate
matter with aerodynamic diameter≤ 2.5 µm (PM 2.5) have been reported. However, EWAS …
matter with aerodynamic diameter≤ 2.5 µm (PM 2.5) have been reported. However, EWAS …
[HTML][HTML] Counteracting aged DNA methylation states to combat ageing and age-related diseases
A Reale, S Tagliatesta, G Zardo, M Zampieri - Mechanisms of Ageing and …, 2022 - Elsevier
DNA methylation (DNAm) overwrites information about multiple extrinsic factors on the
genome. Age is one of these factors. Age causes characteristic DNAm changes that are …
genome. Age is one of these factors. Age causes characteristic DNAm changes that are …
Relative contributions of six lifestyle-and health-related exposures to epigenetic aging: the Coronary Artery Risk Development in Young Adults (CARDIA) Study
Background DNA methylation-based GrimAge acceleration (GrimAA) is associated with a
wide range of age-related health outcomes including cardiovascular disease. Since DNA …
wide range of age-related health outcomes including cardiovascular disease. Since DNA …
Surrounding greenness and biological aging based on DNA methylation: a twin and family study in Australia
Background: High surrounding greenness has many health benefits and might contribute to
slower biological aging. However, very few studies have evaluated this from the perspective …
slower biological aging. However, very few studies have evaluated this from the perspective …
Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans
Background Cardiovascular disease (CVD) is the leading cause of mortality among US
adults. African Americans have higher burden of CVD morbidity and mortality compared to …
adults. African Americans have higher burden of CVD morbidity and mortality compared to …
Contributions of neighborhood social environment and air pollution exposure to Black-White disparities in epigenetic aging
I Yannatos, S Stites, RT Brown, CT McMillan - Plos one, 2023 - journals.plos.org
Racial disparities in many aging-related health outcomes are persistent and pervasive
among older Americans, reflecting accelerated biological aging for Black Americans …
among older Americans, reflecting accelerated biological aging for Black Americans …
DNA hypomethylation promotes learning and memory recovery in a rat model of cerebral ischemia/reperfusion injury
G Shi, J Feng, LY Jian, XY Fan - Neural Regeneration Research, 2023 - journals.lww.com
Cerebral ischemia/reperfusion injury impairs learning and memory in patients. Studies have
shown that synaptic function is involved in the formation and development of memory, and …
shown that synaptic function is involved in the formation and development of memory, and …
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)
Background DNA methylation, an epigenetic mechanism modulated by lifestyle and
environmental factors, may be an important biomarker of complex diseases including …
environmental factors, may be an important biomarker of complex diseases including …
Epigenetic age acceleration markers are associated with physiologic frailty and all-cause mortality in people with human immunodeficiency virus
KK Oursler, VC Marconi, Z Wang, K Xu… - Clinical Infectious …, 2023 - academic.oup.com
Background Biomarkers that provide insight into drivers of aging are needed for people with
human immunodeficiency virus (PWH). The study objective was to determine if epigenetic …
human immunodeficiency virus (PWH). The study objective was to determine if epigenetic …
Associations of DNA methylation algorithms of aging and cancer risk: Results from a prospective cohort study
X Li, B Schöttker, B Holleczek, H Brenner - EBioMedicine, 2022 - thelancet.com
Background Previous studies have shown that three DNA methylation (DNAm) based
algorithms of aging, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge …
algorithms of aging, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge …