The Significant Associations between Epigenetic Clocks and Bladder Cancer Risks
Simple Summary Bladder cancer, an age-related disorder, primarily affects individuals aged
65 and older. Accelerated biological aging, which is linked to increased cancer …
65 and older. Accelerated biological aging, which is linked to increased cancer …
Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study
X Li, Y Zhang, X Gào, B Holleczek, B Schöttker… - …, 2021 - thelancet.com
Abstract Background Three DNA methylation (DNAm) based algorithms, DNAm PhenoAge
acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality …
acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality …
Blood-Based Epigenetic Age Acceleration and Incident Colorectal Cancer Risk: Findings from a Population-Based Case–Control Study
S Malyutina, O Chervova, V Maximov… - International Journal of …, 2024 - mdpi.com
This study investigates the association between epigenetic age acceleration (EAA) derived
from DNA methylation and the risk of incident colorectal cancer (CRC). We utilized data from …
from DNA methylation and the risk of incident colorectal cancer (CRC). We utilized data from …
Analyzing Corin–BNP–NEP Protein Pathway Revealing Differential Mechanisms in AF-Related Ischemic Stroke and No AF-Related Ischemic Stroke
X Shen, N Dong, Y Xu, L Han, R Yang… - Frontiers in Aging …, 2022 - frontiersin.org
Background The incidence of atrial fibrillation (AF)-related stroke increases with aging.
Natriuretic peptides (NPs) family, including Corin-B type natriuretic peptide (BNP)-neprilysin …
Natriuretic peptides (NPs) family, including Corin-B type natriuretic peptide (BNP)-neprilysin …
DNA Methylation age drift is associated with poor outcomes and de-differentiation in papillary and follicular thyroid carcinomas
T Liu, J Wang, Y Xiu, Y Wu, D Xu - Cancers, 2021 - mdpi.com
Simple Summary Normal human tissues contain an epigenetic clock resulting from the age-
dependent DNA methylation signature, which is the so-called DNA methylation (DNAm) age …
dependent DNA methylation signature, which is the so-called DNA methylation (DNAm) age …
Epigenetic age acceleration as an effective predictor of diseases and mortality in the elderly
Q Tan - EBioMedicine, 2021 - thelancet.com
As the nurture side to the nature of genetics, epigenetics offers a link between the genome
and the environment. This is important for studying diseases and complex health traits, such …
and the environment. This is important for studying diseases and complex health traits, such …
From flesh to bones: Multi‐omics approaches in forensic science
N Procopio, A Bonicelli - Proteomics, 2024 - Wiley Online Library
Recent advancements in omics techniques have revolutionised the study of biological
systems, enabling the generation of high‐throughput biomolecular data. These innovations …
systems, enabling the generation of high‐throughput biomolecular data. These innovations …
Nurturing longevity through natural compounds: Where do we stand, and where do we go?
MN Todorova, MS Savova, LV Mihaylova… - Food …, 2024 - Wiley Online Library
The revolution in aging research through the past decade has driven the progress in
interventions that promote longevity. Dissection of the “old” hallmarks of aging has provided …
interventions that promote longevity. Dissection of the “old” hallmarks of aging has provided …
Epigenome-wide DNA methylation in leukocytes and toenail metals: The normative aging study
Background Environmental metal exposures have been associated with multiple deleterious
health endpoints. DNA methylation (DNAm) may provide insight into the mechanisms …
health endpoints. DNA methylation (DNAm) may provide insight into the mechanisms …
The role of epigenetics in cardiovascular disease
Today, cardiovascular pathologies are still the main cause of death and disability worldwide
despite the significant improvements in diagnosis, prevention, and early intervention. The …
despite the significant improvements in diagnosis, prevention, and early intervention. The …