Plant toxic proteins: their biological activities, mechanism of action and removal strategies

E Kocyigit, B Kocaadam-Bozkurt, O Bozkurt… - Toxins, 2023 - mdpi.com
Plants evolve to synthesize various natural metabolites to protect themselves against
threats, such as insects, predators, microorganisms, and environmental conditions (such as …

Bioactive molecules from plants: discovery and pharmaceutical applications

MC Bergonzi, CM Heard, J Garcia-Pardo - Pharmaceutics, 2022 - mdpi.com
The plant kingdom is one of the richest sources of bioactive compounds with pharmaceutical
potential. A special feature of higher plants is their ability to produce a great number of …

Plant Protease Inhibitors as Emerging Antimicrobial Peptide Agents: A Comprehensive Review

MG Parisi, B Ozón, SM Vera González, J García-Pardo… - Pharmaceutics, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are important mediator molecules of the innate defense
mechanisms in a wide range of living organisms, including bacteria, mammals, and plants …

A Multifunctional Trypsin Protease Inhibitor from Yellow Bell Pepper Seeds: Uncovering Its Dual Antifungal and Hypoglycemic Properties

J Cotabarren, B Ozón, S Claver, F Geier, M Rossotti… - Pharmaceutics, 2023 - mdpi.com
Fungal infections are a growing public health concern worldwide and the emergence of
antifungal resistance has limited the number of therapeutic options. Therefore, developing …

Analysis of the antibacterial activity and the total phenolic and flavonoid contents of the moringa oleifera leaf extract as an antimicrobial agent against Pseudomonas …

A Royani, M Hanafi, PDN Lotulung, H Julistiono… - …, 2023 - Wiley Online Library
Pseudomonas aeruginosa is a bacterium that causes metal deterioration by forming biofilms
on metal surfaces. This work was carried out to analyze the antibacterial activity and the …

A Non-competitive Serpin-Like Thrombin Inhibitor Isolated from Moringa oleifera Exhibit a High Affinity for Thrombin

Sawetaji, KK Aggarwal - The Protein Journal, 2023 - Springer
The majority of the clotting factors involved in blood coagulation pathways are serine
proteases and thrombin is one of the key serine proteases involved in blood clotting. Many …

Purification and Identification of Novel Antioxidant Peptides Isolated from Geoffroea decorticans Seeds with Anticoagulant Activity

J Cotabarren, B Ozón, S Claver, J Garcia-Pardo… - Pharmaceutics, 2021 - mdpi.com
Geoffroea decorticans is a xerophilous deciduous tree present in most arid forests of
southern South America, which is commonly used in traditional medicine. The seeds of this …

Synthesis of the Polyhydroquinoline Derivative 4-(2-Chloro-Phenyl)-2, 7, 7-Trimethyl5-oxo-1, 4, 5, 6, 7, 8-Hexahydroquinoline-3-Carboxylic Acid Ethyl Ester …

GHA Machado, MVC Trento, JJ Pinelli, RH Piccoli… - 2021 - researchsquare.com
Multicomponent reactions are extremely relevant in green chemistry. They offer better
conditions than traditional synthesis and are, therefore, used for many organic modifications …

[引用][C] Bioactive Molecules from Plants: Discovery and Pharmaceutical Applications. Pharmaceutics 2022, 14, 2116

MC Bergonzi, CM Heard, J Garcia-Pardo - 2022 - europepmc.org
The plant kingdom is one of the richest sources of bioactive compounds with pharmaceutical
potential. A special feature of higher plants is their ability to produce a great number of …