Alzheimer's disease (AD) is a complex multifactorial disorder that poses a substantial
burden on patients, caregivers, and society. Considering the increased aging population …

Homologous recombination (HR) is a prominent DNA repair pathway maintaining genome
integrity. Mutations in many HR genes lead to cancer predisposition. Paradoxically, the …

Aging is a major risk factor for numerous chronic diseases. Vaccination offers a promising
strategy to combat these age-related diseases by targeting specific antigens and inducing …

The prevalence of age-related diseases has been progressively increasing worldwide. The
pathogenesis of these disorders, including cancer, is closely associated with an age …

Identifying the clinical implications and modifiable and unmodifiable factors of aging
requires the measurement of biological age (BA) and age gap. Leveraging the biomedical …

Non-pituitary growth hormone (npGH) expression is well established in extrapituitary
tissues, but an understanding of the physiological role of npGH remains rather limited. Pro …

Background OCTN1 belongs to the SLC22 family, which includes transporters for cationic,
zwitterionic, and anionic substrates. OCTN1 function and role in cells are still poorly …

The actin cytoskeleton is of fundamental importance for numerous cellular processes,
including intracellular transport, cell plasticity, and cell migration. However, functions of …

Background: Intervertebral disc degeneration (IVDD), which contributes to stenosis of the
spinal segment, commonly causes lower back pain. The process of IVDD degradation …

Gold nanoparticles have been broadly investigated as cancer diagnostic and therapeutic
agents. Gold nanoparticles are a favorable drug delivery vehicle with their unique …