Aging is the result of the accumulation of a wide variety of molecular and cellular damage
over time. This has been associated with a number of features termed hallmarks of aging …

There is a growing awareness that the large number of environmental pollutants we are
exposed to on a daily basis are causing major health problems. Compared to traditional …

Aim The 'rate‐of‐living'theory predicts that life expectancy is a negative function of the rates
at which organisms metabolize. According to this theory, factors that accelerate metabolic …

Bats are potential natural reservoirs for emerging viruses, causing deadly human diseases,
such as COVID-19, MERS, SARS, Nipah, Hendra, and Ebola infections. The fundamental …

Abstract The Fas/FasL system plays a central role in the physiological regulation of
apoptosis and has been implicated in the pathogenesis of several neoplasms and diseases …

Proteome damage plays a major role in aging and age-related neurodegenerative diseases.
Under healthy conditions, molecular quality control mechanisms prevent toxic protein …

Humanity has always sought to live longer and for this, multiple strategies have been tried
with varying results. In this sense, G protein-coupled receptors (GPCRs) may be a good …

Whales are marine creatures known for their enormous size and that live in all the oceans
on earth. One of the oldest known organisms is bowhead whales, which can survive up to …

Hearing loss is a hallmark of aging, typically initially affecting the higher frequencies. In
echolocating bats, the ability to discern high frequencies is essential. However, nothing is …

Mouse and rats are staple model organisms that have been traditionally used for
oncological studies; however, their short lifespan and highly prone to cancers limit their …