[HTML][HTML] The landscape of aging

Y Cai, W Song, J Li, Y Jing, C Liang, L Zhang… - Science China Life …, 2022 - Springer
Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

[HTML][HTML] Stress and telomere shortening: Insights from cellular mechanisms

J Lin, E Epel - Ageing Research Reviews, 2022 - Elsevier
Short telomeres confer risk of degenerative diseases. Chronic psychological stress can lead
to disease through many pathways, and research from in vitro studies to human longitudinal …

Long COVID and the cardiovascular system—elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint …

M Gyöngyösi, P Alcaide, FW Asselbergs… - Cardiovascular …, 2023 - academic.oup.com
Long COVID has become a world-wide, non-communicable epidemic, caused by long-
lasting multiorgan symptoms that endure for weeks or months after SARS-CoV-2 infection …

[HTML][HTML] Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Association between COVID‐19 and telomere length: a bidirectional Mendelian randomization study

D Huang, S Lin, J He, Q Wang… - Journal of medical …, 2022 - Wiley Online Library
Several traditional observational studies suggested an association between COVID‐19 and
leukocyte telomere length (LTL), a biomarker for biological age. However, whether there …

[HTML][HTML] Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

[HTML][HTML] Evidence for biological age acceleration and telomere shortening in COVID-19 survivors

A Mongelli, V Barbi, M Gottardi Zamperla… - International journal of …, 2021 - mdpi.com
The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …

[HTML][HTML] Telomeres and mitochondrial metabolism: implications for cellular senescence and age-related diseases

X Gao, X Yu, C Zhang, Y Wang, Y Sun, H Sun… - Stem cell reviews and …, 2022 - Springer
Cellular senescence is an irreversible cell arrest process, which is determined by a variety of
complicated mechanisms, including telomere attrition, mitochondrial dysfunction, metabolic …

[HTML][HTML] CD8+ T Cell Senescence: Lights and Shadows in Viral Infections, Autoimmune Disorders and Cancer

V Tedeschi, G Paldino, M Kunkl, M Paroli… - International Journal of …, 2022 - mdpi.com
CD8+ T lymphocytes are a heterogeneous class of cells that play a crucial role in the
adaptive immune response against pathogens and cancer. During their lifetime, they …

[HTML][HTML] The pathogenic role of epithelial and endothelial cells in early-phase COVID-19 pneumonia: victims and partners in crime

M Chilosi, V Poletti, C Ravaglia, G Rossi, A Dubini… - Modern Pathology, 2021 - Elsevier
Current understanding of the complex pathogenesis of COVID-19 interstitial pneumonia
pathogenesis in the light of biopsies carried out in early/moderate phase and histology data …