Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Disruption of the epigenetic program of gene expression is a hallmark of cancer that initiates
and propagates tumorigenesis. Altered DNA methylation, histone modifications and ncRNAs …

Methylation patterns in cell-free DNA (cfDNA) have emerged as a promising genomic
feature for detecting the presence of cancer and determining its origin. The purpose of this …

A liquid biopsy is a minimally invasive or non-invasive method to analyze a range of tumor
material in blood or other body fluids, including circulating tumor cells (CTCs), cell-free DNA …

Colorectal cancer (CRC) is one of the main causes of cancer-related morbidity and mortality
across the globe. Although serum biomarkers such as carcinoembryonic antigen (CEA) and …

Background Detection of circulating tumor DNA (ctDNA) is a minimally invasive and
convenient blood-based screening strategy that may increase effectiveness of colorectal …

Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …

Colorectal cancer (CRC) is one of the most common cancers worldwide. The diagnosis,
prognosis and therapeutic monitoring of CRC depends largely on tissue biopsy. However …

Background Circulating tumour DNA (ctDNA) has been established as a promising
(prognostic) biomarker with the potential to personalise treatment in cancer patients. The …

The low positive predictive value (PPV) of early screening of nasopharyngeal carcinoma
(NPC) is the problems that need to be solved urgently. The combination of cell‐free DNA …