The burden of influenza and the role of influenza vaccination in adults aged 50-64 years: A summary of available evidence

S Marchi, E Fallani, M Salvatore… - Human Vaccines & …, 2023 - Taylor & Francis
Influenza is a vaccine-preventable disease and a global public health problem. Although
most national influenza vaccination recommendations focus on subjects aged≥ 65 years …

An impact of age on respiratory syncytial virus infection in air-liquid-interface culture bronchial epithelium

K Ito, L Daly, M Coates - Frontiers in Medicine, 2023 - frontiersin.org
Background Elderly people are known to be vulnerable to virus infection. However, this has
not been appropriately tested in in vitro studies due to a lack of appropriate virus infection …

Immunology of pregnancy and reproductive health in autoimmune rheumatic diseases. Update from the 11th International Conference on Reproduction, Pregnancy …

L Andreoli, CB Chighizola, L Iaccarino, A Botta… - Autoimmunity …, 2023 - Elsevier
Autoimmune rheumatic diseases (ARD) can affect women and men during fertile age,
therefore reproductive health is a priority issue in rheumatology. Many topics need to be …

Vaccine-preventable diseases in older adults

M Al-Jabri, C Rosero, EA Saade - Infectious Disease Clinics, 2023 - id.theclinics.com
With older age, humans are at a progressively higher risk of infection and increased
morbidity and mortality related to vaccine-preventable infections, such as influenza …

[HTML][HTML] Immunosenescence is a therapeutic target for frailty in older adults: a narrative review

H Jia, W Huang, C Liu, S Tang, J Zhang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Immunosenescence is a therapeutic target for frailty in older adults: a narrative review - PMC
Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Reduced immunogenicity of a live Salmonella enterica serovar Typhimurium vaccine in aged mice

JC Allen, FR Toapanta, SM Baliban, MB Sztein… - Frontiers in …, 2023 - frontiersin.org
Introduction Non-typhoidal Salmonella (NTS) is responsible for a high burden of foodborne
infections and deaths worldwide. In the United States, NTS infections are the leading cause …

Respiratory Syncytial Virus Vaccines: Analysis of Pre-Marketing Clinical Trials for Immunogenicity in the Population over 50 Years of Age

G Papazisis, X Topalidou, G Gioula, PA González… - Vaccines, 2024 - mdpi.com
Immunosenescence refers to age-related alterations in immune system function affecting
both the humoral and cellular arm of immunity. Understanding immunosenescence and its …

A low dose of RBD and TLR7/8 agonist displayed on influenza virosome particles protects rhesus macaque against SARS-CoV-2 challenge

G Koopman, M Amacker, T Stegmann, EJ Verschoor… - Scientific Reports, 2023 - nature.com
Influenza virosomes serve as antigen delivery vehicles and pre-existing immunity toward
influenza improves the immune responses toward antigens. Here, vaccine efficacy was …

[HTML][HTML] Oxidative stress and endogenous DNA damage in blood mononuclear cells may predict anti-SARS-CoV-2 antibody titers after vaccination in older adults

PA Ntouros, E Kravvariti, NI Vlachogiannis… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Immune senescence in the elderly has been associated with chronic oxidative stress and
DNA damage accumulation. Herein we tested the hypothesis that increased endogenous …

[HTML][HTML] Screening of antibacterial compounds with novel structure from the FDA approved drugs using machine learning methods

WX Li, X Tong, PP Yang, Y Zheng, JH Liang… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Bacterial infection is one of the most important factors affecting the human life span. Elderly
people are more harmed by bacterial infections due to their deficits in immunity. Because of …