Recent advances in organoid development and applications in disease modeling

S Rauth, S Karmakar, SK Batra… - Biochimica et Biophysica …, 2021 - Elsevier
An improved understanding of stem cell niches, organogenesis, and disease models has
paved the way for developing a three-dimensional (3D) organoid culture system. Organoid …

3D printing of pharmaceutical application: drug screening and drug delivery

G Gao, M Ahn, WW Cho, BS Kim, DW Cho - Pharmaceutics, 2021 - mdpi.com
Advances in three-dimensional (3D) printing techniques and the development of tailored
biomaterials have facilitated the precise fabrication of biological components and complex …

In vitro and in vivo models for studying SARS-CoV-2, the etiological agent responsible for COVID-19 pandemic

RB Rosa, WM Dantas, JCF do Nascimento… - Viruses, 2021 - mdpi.com
The emergence and rapid worldwide spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has prompted the scientific community to rapidly develop in …

Long COVID and long chain fatty acids (LCFAs): Psychoneuroimmunity implication of omega-3 LCFAs in delayed consequences of COVID-19

CP Yang, CM Chang, CC Yang, CM Pariante… - Brain, Behavior, and …, 2022 - Elsevier
The global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
led to the lasting pandemic of coronavirus disease 2019 (COVID-19) and the post-acute …

Advances in understanding neuropathogenesis of rift valley fever virus

KA Connors, AL Hartman - Annual review of virology, 2022 - annualreviews.org
Rift Valley fever virus (RVFV) is an emerging arboviral pathogen that causes disease in both
livestock and humans. Severe disease manifestations of Rift Valley fever (RVF) in humans …

Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?

A Verkhratsky, Q Li, S Melino, G Melino, Y Shi - Biology direct, 2020 - Springer
Abstract The pandemic of Coronavirus Disease 2019 (COVID-19) presents the world with
the medical challenge associated with multifactorial nature of this pathology. Indeed COVID …

Blood biomarkers for detection of brain injury in COVID-19 patients

ST DeKosky, PM Kochanek, AB Valadka… - Journal of …, 2021 - liebertpub.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus attacks multiple
organs of coronavirus disease 2019 (COVID-19) patients, including the brain. There are …

Human organoids and organs‐on‐chips for addressing COVID‐19 challenges

Y Wang, P Wang, J Qin - Advanced Science, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), poses an imminent threat to our lives. Although …

Involvement of the nervous system in COVID-19: The bell should toll in the brain

S Satarker, M Nampoothiri - Life sciences, 2020 - Elsevier
The world is fuming at SARS-CoV-2 for being the culprit for causing the devastating COVID-
19, claiming millions of lives across the globe in the form of respiratory disorders. But lesser …

Human 3D brain organoids: steering the demolecularization of brain and neurological diseases

YK Adlakha - Cell Death Discovery, 2023 - nature.com
Understanding of human brain development, dysfunction and neurological diseases has
remained limited and challenging due to inability to recapitulate human brain-specific …