Background This large-scale analysis pools individual data about the Clinical Frailty Scale
(CFS) to predict outcome in the intensive care unit (ICU). Methods A systematic search …

This essay considers the factors that have contributed to very high COVID-19 mortality in
longer-term care facilities (LTCFs). We compare the demographic characteristics of LTCF …

Background: This study monitored total anti-SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) RBD (receptor-binding domain) antibodies levels in a large …

Objectives To evaluate, in a cohort of adults aged≥ 80 years, the overlapping effect of
clinical severity, comorbidities, cognitive impairment, and frailty, for the in-hospital death risk …

Introduction The incidence of major trauma in older people is increasing. Frailty is likely to
be a factor that influences the outcomes of trauma. We conducted a systematic review …

Background Observational data during the pandemic have demonstrated mixed
associations between frailty and mortality. Aim To examine associations between frailty and …

Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …

Background The concept of frailty provides an age-independent, easy-to-use tool for risk
stratification. We aimed to summarize the evidence on the efficacy of frailty tools in risk …

Objectives: This study aimed to assess the effects of frailty and the perceived quality of life
(QOL) on the long-term survival (at least 1 year) of patients≥ 80 years hospitalized for …

Introduction: Frailty, a measure of biological aging, has been linked to worse COVID-19
outcomes. However, as the mortality differs across the COVID-19 waves, it is less clear …