DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Cancer initiation and proliferation is regulated by both epigenetic and genetic events with
epigenetic modifications being increasingly identified as important targets for cancer …

Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Colorectal cancer (CRC) is one of the most common cancer worldwide and results from the
accumulation of mutations and epimutations in colonic mucosa cells ultimately leading to …

BACKGROUND Epi proColon® is a new blood-based colorectal cancer (CRC) screening
test designed to determine the methylation status of a promoter region of the SEPT9 (septin …

Background: Colorectal cancer (CRC) follows a protracted stepwise progression, from
benign adenomas to malignant adenocarcinomas. If detected early, 90% of deaths are …

The purpose of this systematic review was to compare the diagnostic ability of blood markers
for colorectal cancer (CRC). A systematic review of the literature for diagnostic blood …