Rosmarinic acid-loaded polymeric nanoparticles prepared by low-energy nano-emulsion templating: Formulation, biophysical characterization, and in vitro studies
J García-Melero, JJ López-Mitjavila, MJ García-Celma… - Materials, 2022 - mdpi.com
Rosmarinic acid (RA), a caffeic acid derivative, has been loaded in polymeric nanoparticles
made up of poly (lactic-co-glycolic acid)(PLGA) through a nano-emulsion templating process …
made up of poly (lactic-co-glycolic acid)(PLGA) through a nano-emulsion templating process …
Nephroprotective effects of curcumin loaded chitosan nanoparticles in cypermethrin induced renal toxicity in rabbits
Cypermethrin, a pyrethroid insecticide, may cause several adverse effects including
nephrotoxicity. Curcumin is a nutraceutical with many pharmacological effects including …
nephrotoxicity. Curcumin is a nutraceutical with many pharmacological effects including …
Development and Evaluation of Letrozole-Loaded Hyaluronic Acid/Chitosan-Coated Poly(d,l-lactide-co-glycolide) Nanoparticles
Purpose Letrozole (LTZ), an aromatase inhibitor with poor aqueous solubility, is used as the
first line treatment for hormonal sensitive breast cancer in postmenopausal women. The …
first line treatment for hormonal sensitive breast cancer in postmenopausal women. The …
Poly(lactic-co-glycolic acid) Nanoparticles for the Encapsulation and Gastrointestinal Release of Vitamin B9 and Vitamin B12
MJ Ramalho, JA Loureiro… - ACS Applied Nano …, 2021 - ACS Publications
Deficiencies of vitamin B9 (VB9) and vitamin B12 (VB12) are very common among aged
adults due to their poor oral bioavailability. However, the poor stability of these vitamins …
adults due to their poor oral bioavailability. However, the poor stability of these vitamins …
An innovative formulation based on nanostructured lipid carriers for imatinib delivery: Pre-formulation, cellular uptake and cytotoxicity studies
E Gundogdu, ES Demir, M Ekinci, E Ozgenc… - Nanomaterials, 2022 - mdpi.com
Imatinib (IMT) is a tyrosine kinase enzyme inhibitor and extensively used for the treatment of
gastrointestinal stromal tumors (GISTs). A nanostructured lipid carrier system (NLCS) …
gastrointestinal stromal tumors (GISTs). A nanostructured lipid carrier system (NLCS) …
Propitious maneuvering for delivery of the phytopharmaceutical “apocynin” to induced fulminant hepatitis in BALB/c mice: In vitro and in vivo assessments
Apocynin (APO), a specific nicotinamide adenine dinucleotide phosphate-oxidase (NADPH-
oxidase, NOX) inhibitor, has recently emerged as a bioactive phytochemical with eminent …
oxidase, NOX) inhibitor, has recently emerged as a bioactive phytochemical with eminent …
A top-down technique to improve the solubility and bioavailability of aceclofenac: in vitro and in vivo studies
R Narayan, A Pednekar, D Bhuyan… - International journal …, 2017 - Taylor & Francis
The aim of the present work was to tackle the solubility issue of a biopharmaceutics
classification system (BCS)-II drug, aceclofenac. Although a number of attempts to increase …
classification system (BCS)-II drug, aceclofenac. Although a number of attempts to increase …
Synthesis and appraisal of dalbergin-loaded PLGA nanoparticles modified with galactose against hepatocellular carcinoma: In-vitro, pharmacokinetic, and in-silico …
AK Gautam, P Kumar, B Maity, G Routholla… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a common malignancy which affects a substantial
number of individuals all over the globe. It is the third primary cause of death among persons …
number of individuals all over the globe. It is the third primary cause of death among persons …
Formulation design, statistical optimization and in vitro biological activities of nano-emulsion containing essential oil from cotton-lavender (Santolina …
SM AlMotwaa, WA Al-Otaibi - Journal of Drug Delivery Science and …, 2022 - Elsevier
Santolina chamaecyparissus is an aromatic medicinal plant belonging to Asteraceae family.
The current study was aimed at optimizing the conditions for the production of Santolina …
The current study was aimed at optimizing the conditions for the production of Santolina …
PHBV/PLGA nanoparticles for enhanced delivery of 5-fluorouracil as promising treatment of colon cancer
S Handali, E Moghimipour, M Rezaei… - Pharmaceutical …, 2020 - Taylor & Francis
Fluorouracil (5-FU) is one of the most widely used agents in the first-line chemotherapy for
colon cancer. However, clinical use of 5-FU is limited because of the low efficacy of drug …
colon cancer. However, clinical use of 5-FU is limited because of the low efficacy of drug …