In recent years, viruses similar to those that cause serious disease in humans and other
mammals have been detected in apparently healthy bats. These include filoviruses …

The idea that senescent cells are causally involved in aging has gained strong support from
findings that the removal of such cells alleviates many age‐related diseases and extends …

Big, time-scaled phylogenies are fundamental to connecting evolutionary processes to
modern biodiversity patterns. Yet inferring reliable phylogenetic trees for thousands of …

Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity
and unique immunity. High-quality genomes are crucial for understanding the molecular …

Mammals differ more than 100-fold in maximum lifespan. Here, we conducted comparative
transcriptomics on 26 species with diverse lifespans. We identified thousands of genes with …

INTRODUCTION How novel protein architectures evolve remains poorly understood. The
rearrangement of domains with preexisting functions into new composite architectures …

Aging negatively impacts vitality and health. Many genetic pathways that regulate aging
were discovered in invertebrates. However, the genetics of aging is more complex in …

For centuries, people believed that bats possessed sinister powers. Bats are thought to be
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …

Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …