Bacteriophages (phages) represent a unique category of viruses with a remarkable ability to
selectively infect host bacteria, characterized by their assembly from proteins and nucleic …

Cisplatin is a chemotherapy drug widely used in cancer treatment. Alongside its clinical
benefits, however, it may inflict intolerable toxicity and other adverse effects on healthy …

Extracellular vesicles (EVs) are membrane-bound vesicles that can be released by all cell
types. They may have different biogenesis, physical features, and cargo. EVs are important …

One of the main reasons we have not been able to cure cancers is that drugs select for drug-
resistant cancer cells. Pest managers face similar challenges with pesticides selecting for …

Leading anti-tumour therapeutic strategies typically involve surgery and radiotherapy for
locally advanced (non-metastatic) cancers, while hormone therapy, chemotherapy, and …

Fatty acid synthase (FASN) is the rate-limiting enzyme for the de novo synthesis of fatty acids
in the cytoplasm of tumour cells. Many tumour cells express high levels of FASN, and its …

Nowadays, drug resistance (DR) in gastrointestinal (GI) cancers, as the main reason for
cancer-related mortality worldwide, has become a serious problem in the management of …

Natural products have played a significant role throughout history in the prevention and
treatment of numerous diseases, particularly cancers. As a natural product primarily derived …

Despite ongoing advancements in cancer treatment, the emergence of primary and acquired
resistance poses a significant challenge for both traditional chemotherapy and immune …

Background More and more studies have demonstrated that potassium channel
tetramerization domain-containing 5 (KCTD5) plays an important role in the development of …