Unleashing the power of immune checkpoints: post-translational modification of novel molecules and clinical applications
J Wang, Y Wang, X Jiang, M Xu, M Wang, R Wang… - Cancer Letters, 2024 - Elsevier
Immune checkpoint molecules play a pivotal role in the initiation, regulation, and termination
of immune responses. Tumor cells exploit these checkpoints to dampen immune cell …
of immune responses. Tumor cells exploit these checkpoints to dampen immune cell …
Exosome-mediated communication between gastric cancer cells and macrophages: implications for tumor microenvironment
Y Qiu, G Lu, N Li, Y Hu, H Tan, C Jiang - Frontiers in Immunology, 2024 - frontiersin.org
Gastric cancer (GC) is a malignant neoplasm originating from the epithelial cells of the
gastric mucosa. The pathogenesis of GC is intricately linked to the tumor microenvironment …
gastric mucosa. The pathogenesis of GC is intricately linked to the tumor microenvironment …
CD155 as an emerging target in tumor immunotherapy
JW Wu, Y Liu, XJ Dai, HM Liu, YC Zheng… - International …, 2024 - Elsevier
CD155 is an immunoglobulin-like protein overexpressed in almost all the tumor cells, which
not only promotes proliferation, adhesion, invasion, and migration of tumor cells, but also …
not only promotes proliferation, adhesion, invasion, and migration of tumor cells, but also …
[HTML][HTML] Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming
T Yu, Z Liu, Q Tao, X Xu, X Li, Y Li, M Chen, R Liu… - Cancer Letters, 2024 - Elsevier
Immunotherapy, especially immune checkpoint inhibitors, has revolutionized clinical
practice within the last decade. However, primary and secondary resistance to …
practice within the last decade. However, primary and secondary resistance to …
TIGIT: A potential immunotherapy target for gynecological cancers
S Jiang, W Wang, Y Yang - Pathology-Research and Practice, 2024 - Elsevier
Gynecological cancer represents a significant global health challenge, and conventional
treatment modalities have demonstrated limited efficacy. However, recent investigations into …
treatment modalities have demonstrated limited efficacy. However, recent investigations into …
Herb pair of Huangqi‐Danggui exerts anti‐tumor immunity to breast cancer by upregulating PIK3R1
HX Liu, L Lian, LL Hou, CX Liu, JH Ren… - Animal Models and …, 2024 - Wiley Online Library
Abstract Background According to traditional Chinese medicine (TCM), drugs
supplementing the vital energy, Qi, can eliminate tumors by restoring host immunity. The …
supplementing the vital energy, Qi, can eliminate tumors by restoring host immunity. The …